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Catalog Number:
37080
CAS Number:
1128181-23-6
Nα -Fmoc- Nε -tetradecanoyl-L-lysine
Purity:
99 - 100% (Assay by titration)
Synonym(s):
Fmoc-L-Lys(myristoyl)-OH
Documents
$62.29 /250MG
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Product Information

Na-Fmoc-Ne-tetradecanoyl-L-lysine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its stability and ease of removal under mild conditions, making it an ideal choice for solid-phase peptide synthesis. The tetradecanoyl chain enhances the lipophilicity of the molecule, facilitating its incorporation into lipid-based formulations and improving the bioavailability of therapeutic peptides.

Researchers and industry professionals can leverage Na-Fmoc-Ne-tetradecanoyl-L-lysine in various applications, including the development of targeted drug delivery systems and the synthesis of bioactive peptides. Its unique properties allow for the creation of more effective therapeutic agents with enhanced stability and solubility. This compound is particularly beneficial in the fields of medicinal chemistry and biochemistry, where the synthesis of complex peptides is essential for advancing drug discovery and development.

Synonyms
Fmoc-L-Lys(myristoyl)-OH
CAS Number
1128181-23-6
Purity
99 - 100% (Assay by titration)
Molecular Formula
C35H50N2O5
Molecular Weight
578.8
MDL Number
MFCD30725756
PubChem ID
74410182
Melting Point
139 - 143 ?C
Appearance
White crystalline powder or white powder
Optical Rotation
[a]20D = 15 ± 1 ° (C=1 in CHCl3
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-L-Lys(myristoyl)-OH
CAS Number
1128181-23-6
Purity
99 - 100% (Assay by titration)
Molecular Formula
C35H50N2O5
Molecular Weight
578.8
MDL Number
MFCD30725756
PubChem ID
74410182
Melting Point
139 - 143 ?C
Appearance
White crystalline powder or white powder
Optical Rotation
[a]20D = 15 ± 1 ° (C=1 in CHCl3
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na -Fmoc- Ne -tetradecanoyl-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective Fmoc group allows for selective deprotection, facilitating the assembly of complex peptide sequences.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. The tetradecanoyl modification enhances membrane permeability, making it useful for developing therapeutics that require efficient cellular uptake.
  • Bioconjugation: This chemical is employed in bioconjugation processes, where it helps attach peptides to various biomolecules. This application is vital in creating targeted drug delivery systems and improving the efficacy of therapeutic agents.
  • Protein Engineering: Researchers utilize this compound in protein engineering to modify lysine residues, which can alter protein function and stability. This is particularly beneficial in the development of novel enzymes or antibodies.
  • Cosmetic Formulations: The compound finds application in the cosmetic industry, where it is used in formulations aimed at enhancing skin penetration of active ingredients, thereby improving the effectiveness of skincare products.

Citations