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Catalog Number:
33495
CAS Number:
2250436-42-9(net)
Nα -Fmoc-D-Lysine tert-butyl ester hydrochloride
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Lys-OtBu·HCl
Documents
$135.90 /100MG
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Product Information

Na -Fmoc-D-Lysine tert-butyl ester hydrochloride is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is essential for the selective protection of the amino group during the synthesis of peptides. Its tert-butyl ester form enhances solubility and stability, making it an ideal choice for researchers focused on complex peptide structures.

In the pharmaceutical industry, Na -Fmoc-D-Lysine tert-butyl ester hydrochloride is particularly valuable for developing therapeutic peptides, including those used in cancer treatment and hormone replacement therapies. Its unique properties allow for efficient coupling reactions and facilitate the synthesis of modified peptides with improved bioactivity. Researchers appreciate its reliability and effectiveness in producing high-purity compounds, which are crucial for advancing drug discovery and development.

Synonyms
Fmoc-D-Lys-OtBu·HCl
CAS Number
2250436-42-9(net)
Purity
≥ 99% (HPLC)
Molecular Formula
C25H32N2O4·HCl
Molecular Weight
461.0
MDL Number
MFCD32200864
PubChem ID
58402449
Melting Point
94 - 100 ?C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = 15.5 - 17.0 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-D-Lys-OtBu·HCl
CAS Number
2250436-42-9(net)
Purity
≥ 99% (HPLC)
Molecular Formula
C25H32N2O4·HCl
Molecular Weight
461.0
MDL Number
MFCD32200864
PubChem ID
58402449
Melting Point
94 - 100 ?C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = 15.5 - 17.0 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na -Fmoc-D-Lysine tert-butyl ester hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It plays a crucial role in the development of peptide-based drugs, offering a means to modify peptide structures for enhanced stability and bioactivity, which is essential in pharmaceutical research.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach peptides to other biomolecules, facilitating the design of targeted drug delivery systems in cancer therapy.
  • Protein Engineering: Researchers utilize this chemical to modify lysine residues in proteins, which can improve protein functionality and stability, making it valuable in biotechnology applications.
  • Diagnostics: It is also applied in the development of diagnostic tools, where modified peptides can be used as biomarkers for disease detection, enhancing the sensitivity and specificity of tests.

Citations