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Catalog Number:
30545
CAS Number:
1128181-16-7
N-Fmoc-N-Octanoyl-L-Lysine
Purity:
≥ 99% (Assay by titration, HPLC)
Synonym(s):
Fmoc-L-Lys(Octanoyl)-OH
Documents
$62.40 /100MG
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Product Information

Na-Fmoc-Ne-Octanoyl-L-Lysine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its stability and ease of removal under mild conditions, making it an ideal choice for solid-phase peptide synthesis. The octanoyl modification enhances its lipophilicity, allowing for improved membrane permeability, which is particularly beneficial in the design of bioactive peptides and pharmaceutical agents. Researchers in the fields of medicinal chemistry and biochemistry can leverage this compound for the development of targeted drug delivery systems and novel therapeutic peptides.

This compound is especially useful in the synthesis of peptide-based therapeutics, where its unique properties facilitate the creation of compounds with enhanced biological activity and stability. Its application extends to the development of peptide vaccines and other biopharmaceuticals, where the ability to modify peptide structures can lead to improved efficacy and reduced side effects. With its favorable characteristics, Na-Fmoc-Ne-Octanoyl-L-Lysine stands out as a valuable tool for researchers aiming to innovate in peptide chemistry and drug formulation.

Synonyms
Fmoc-L-Lys(Octanoyl)-OH
CAS Number
1128181-16-7
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C29H38N2O5
Molecular Weight
494.6
MDL Number
MFCD24849706
PubChem ID
74410103
Melting Point
132 - 140 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = - 13 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Lys(Octanoyl)-OH
CAS Number
1128181-16-7
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C29H38N2O5
Molecular Weight
494.6
MDL Number
MFCD24849706
PubChem ID
74410103
Melting Point
132 - 140 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = - 13 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-Octanoyl-L-Lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, particularly in enhancing the stability and bioavailability of drug candidates.
  • Bioconjugation: The chemical is used in bioconjugation processes, facilitating the attachment of peptides to various biomolecules, which is essential in creating targeted drug delivery systems.
  • Research in Cancer Therapies: Its applications extend to cancer research, where it aids in the design of peptide ligands that can selectively bind to cancer cells, improving treatment efficacy.
  • Protein Engineering: This compound is valuable in protein engineering, allowing scientists to modify proteins for better functionality or to study protein interactions in biological systems.

Citations