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Catalog Number:
30544
CAS Number:
359780-63-5
N-Fmoc-N-(2-nitrobenzenesulfonyl)-L-lysine
Purity:
≥ 99% (HPLC)
Synonym(s):
Nα-Fmoc-Nε-Nosyl-L-lysine, Fmoc-L-Lys(Ns)-OH
Documents
$75.50 /250MG
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Product Information

Na-Fmoc-Ne-Nosyl-L-lysine is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for researchers in the fields of medicinal chemistry and biochemistry. The incorporation of the Nosyl (2-nitrophenylsulfonyl) group enhances its reactivity and stability, facilitating the formation of complex peptide structures.

Researchers and industry professionals appreciate Na-Fmoc-Ne-Nosyl-L-lysine for its ability to improve the yield and purity of synthesized peptides, particularly in the development of therapeutic agents and biologically active compounds. Its unique properties make it an ideal choice for applications in drug discovery, protein engineering, and the development of targeted therapies. By utilizing this compound, scientists can streamline their workflows and achieve more reliable results in their research endeavors.

Synonyms
Nα-Fmoc-Nε-Nosyl-L-lysine, Fmoc-L-Lys(Ns)-OH
CAS Number
359780-63-5
Purity
≥ 99% (HPLC)
Molecular Formula
C27H27N3O8S
Molecular Weight
553.6
MDL Number
MFCD22989438
PubChem ID
138109651
Melting Point
56-62 °C
Appearance
White crystalline or off-white amorphous powder
Optical Rotation
[a]D20 = - 11 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Nα-Fmoc-Nε-Nosyl-L-lysine, Fmoc-L-Lys(Ns)-OH
CAS Number
359780-63-5
Purity
≥ 99% (HPLC)
Molecular Formula
C27H27N3O8S
Molecular Weight
553.6
MDL Number
MFCD22989438
PubChem ID
138109651
Melting Point
56-62 °C
Appearance
White crystalline or off-white amorphous powder
Optical Rotation
[a]D20 = - 11 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-Nosyl-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions and the formation of complex structures. Its stability under various conditions makes it a preferred choice for researchers in organic chemistry.
  • Drug Development: In pharmaceutical research, it is used to create novel drug candidates by modifying peptide sequences, which can lead to improved efficacy and reduced side effects in therapeutic applications.
  • Bioconjugation: The compound facilitates the attachment of biomolecules to surfaces or other molecules, enhancing the development of targeted drug delivery systems and diagnostic tools in biotechnology.
  • Protein Engineering: Researchers utilize it in the design of modified proteins, which can exhibit enhanced stability and activity, crucial for applications in enzyme technology and therapeutic proteins.
  • Research in Cancer Therapeutics: Its role in synthesizing peptide-based inhibitors allows for the exploration of new cancer treatments, providing a pathway for developing more effective therapies with fewer side effects.

Citations