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Catalog Number:
30531
CAS Number:
1301706-55-7
N-Fmoc-N-Palmitoyl-D-Lysine
Purity:
98 - 100% (Assay by titration)
Synonym(s):
Fmoc-D-Lys(Palm)-OH
Documents
$101.75 /100MG
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Product Information

Na-Fmoc-Ne-Palmitoyl-D-Lysine is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amine functionalities during solid-phase peptide synthesis. The palmitoyl group enhances its lipophilicity, making it particularly valuable in formulating lipid-based drug delivery systems. Researchers appreciate its ability to improve the stability and bioavailability of therapeutic peptides, facilitating their application in various biomedical fields, including cancer therapy and vaccine development.

This compound's unique structure allows for easy incorporation into peptides, enabling the design of novel therapeutics with enhanced pharmacological properties. Its application extends to the development of targeted delivery systems, where the palmitoyl moiety aids in cellular uptake, thus increasing the efficacy of the drug. Na-Fmoc-Ne-Palmitoyl-D-Lysine stands out for its dual functionality, combining the benefits of both Fmoc chemistry and lipidation, making it an essential tool for researchers and industry professionals focused on advancing peptide-based therapies.

Synonyms
Fmoc-D-Lys(Palm)-OH
CAS Number
1301706-55-7
Purity
98 - 100% (Assay by titration)
Molecular Formula
C37H54N2O5
Molecular Weight
606.8
MDL Number
MFCD08274507
PubChem ID
75627338
Melting Point
137 - 145 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 8.5 - 12.0 º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Lys(Palm)-OH
CAS Number
1301706-55-7
Purity
98 - 100% (Assay by titration)
Molecular Formula
C37H54N2O5
Molecular Weight
606.8
MDL Number
MFCD08274507
PubChem ID
75627338
Melting Point
137 - 145 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = 8.5 - 12.0 º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-Palmitoyl-D-Lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice for researchers in organic chemistry.
  • Drug Delivery Systems: Its palmitoyl group enhances membrane permeability, making it useful in formulating drug delivery systems that can effectively transport therapeutic agents across cell membranes.
  • Bioconjugation: The compound can be employed in bioconjugation techniques, linking biomolecules to surfaces or other molecules, which is essential in the development of biosensors and diagnostic tools.
  • Cosmetic Formulations: Due to its skin-penetrating properties, it is incorporated into cosmetic products aimed at enhancing skin absorption and delivering active ingredients more effectively.
  • Research in Cell Biology: This chemical is valuable in studying cellular processes, particularly in understanding how peptides interact with cell membranes, which can lead to advancements in therapeutic strategies.

Citations