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Catalog Number:
30515
CAS Number:
473430-12-5
Na-Azido-Ne-Fmoc-L-lysine
Purity:
≥ 99% (Assay by titration, HPLC, TLC)
Synonym(s):
(S-(-)-2-Azido-6-(Fmoc-amino)hexanoic acid, N3-L-Lys(Fmoc)-OH
Documents
$58.39 /100MG
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Product Information

Na-Azido-Ne-Fmoc-L-lysine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and bioconjugation applications. This compound features an azido group, which allows for click chemistry reactions, making it an invaluable tool for researchers in the fields of medicinal chemistry and biochemistry. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group provides stability during synthesis and can be easily removed under mild conditions, facilitating the production of complex peptides.

Researchers and industry professionals can leverage Na-Azido-Ne-Fmoc-L-lysine for the development of targeted drug delivery systems, as well as in the creation of novel biomaterials. Its unique properties enable the incorporation of azide functionalities into peptides, which can be further modified for specific applications, such as in the development of therapeutics or diagnostic tools. This compound stands out due to its ease of use and compatibility with various coupling methods, making it a preferred choice for those looking to enhance their peptide synthesis workflows.

Synonyms
(S-(-)-2-Azido-6-(Fmoc-amino)hexanoic acid, N3-L-Lys(Fmoc)-OH
CAS Number
473430-12-5
Purity
≥ 99% (Assay by titration, HPLC, TLC)
Molecular Formula
C21H22N4O4
Molecular Weight
394.4
MDL Number
MFCD22989453
PubChem ID
12161720
Melting Point
71 - 76 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -29 ± 1 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(S-(-)-2-Azido-6-(Fmoc-amino)hexanoic acid, N3-L-Lys(Fmoc)-OH
CAS Number
473430-12-5
Purity
≥ 99% (Assay by titration, HPLC, TLC)
Molecular Formula
C21H22N4O4
Molecular Weight
394.4
MDL Number
MFCD22989453
PubChem ID
12161720
Melting Point
71 - 76 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -29 ± 1 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Azido-Ne-Fmoc-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities.
  • Click Chemistry: Its azido group enables efficient click chemistry reactions, facilitating the attachment of various biomolecules, which is crucial in drug development and bioconjugation studies.
  • Biological Research: Used in the study of protein interactions and modifications, it helps scientists understand cellular mechanisms and develop targeted therapies.
  • Drug Delivery Systems: The compound can be incorporated into drug delivery vehicles, enhancing the specificity and efficacy of therapeutic agents in treating diseases.
  • Fluorescent Labeling: By attaching fluorescent tags through its reactive groups, it aids in visualizing biological processes, which is essential for imaging studies in cellular biology.

Citations