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Catalog Number:
26454
CAS Number:
122832-81-9
N-Trityl-N-Fmoc-L-lysine
Purity:
≥ 98% (HPLC)
Synonym(s):
Trt-L-Lys(Fmoc)-OH
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Product Information

Na-Trityl-Ne-Fmoc-L-lysine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a trityl protecting group and a fluorenylmethoxycarbonyl (Fmoc) moiety, making it an essential building block for the construction of complex peptides. Its unique structure allows for selective deprotection under mild conditions, which is particularly advantageous in the synthesis of sensitive biomolecules. Researchers and industry professionals appreciate its stability and compatibility with various coupling reagents, facilitating efficient peptide assembly.

In practical applications, Na-Trityl-Ne-Fmoc-L-lysine is commonly employed in the production of therapeutic peptides, including those used in cancer treatment and hormone replacement therapies. Its ability to enhance solubility and improve the pharmacokinetic properties of peptides makes it a valuable asset in pharmaceutical research. Additionally, its use in solid-phase peptide synthesis streamlines the process, allowing for higher yields and purities. This compound stands out for its reliability and effectiveness, making it a preferred choice among chemists and researchers in the field.

Synonyms
Trt-L-Lys(Fmoc)-OH
CAS Number
122832-81-9
Purity
≥ 98% (HPLC)
Molecular Formula
C40H38N2O4
Molecular Weight
610.75
MDL Number
MFCD05663751
PubChem ID
14283987
Melting Point
165 - 175 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = + 35 to + 38.5 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Trt-L-Lys(Fmoc)-OH
CAS Number
122832-81-9
Purity
≥ 98% (HPLC)
Molecular Formula
C40H38N2O4
Molecular Weight
610.75
MDL Number
MFCD05663751
PubChem ID
14283987
Melting Point
165 - 175 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = + 35 to + 38.5 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Trityl-Ne-Fmoc-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for various applications in biochemistry and pharmaceuticals.
  • Drug Development: It plays a significant role in drug formulation, particularly in designing peptide-based therapeutics that target specific biological pathways, enhancing the efficacy of treatments.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach drugs or imaging agents to biomolecules, improving the delivery and targeting of therapies.
  • Research in Protein Engineering: It aids in the modification of proteins, allowing scientists to study protein interactions and functions, which is crucial for understanding diseases and developing new treatments.
  • Development of Diagnostic Tools: This chemical contributes to the creation of diagnostic assays, enhancing the sensitivity and specificity of tests used in clinical settings.

Citations