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Catalog Number:
05734
CAS Number:
148083-64-1
N-Fmoc-N-2,4-dinitrophenyl-L-lysine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Lys(Dnp)-OH
Documents
$105.00 /250MG
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Product Information

Na-Fmoc-Ne-2,4-dinitrophenyl-L-lysine is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This amino acid derivative features a protective Fmoc group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis, making it an essential tool for researchers in the fields of medicinal chemistry and biotechnology. The presence of the 2,4-dinitrophenyl moiety enhances its utility in various labeling and detection applications, allowing for the development of targeted therapeutics and diagnostic agents.

This compound is particularly advantageous for researchers looking to create complex peptides with specific functionalities. Its unique structure not only aids in the synthesis of peptides with enhanced stability and bioactivity but also allows for the incorporation of fluorescent or chromogenic tags, which are crucial for tracking and analyzing biological interactions. With its robust performance in peptide synthesis and bioconjugation, Na-Fmoc-Ne-2,4-dinitrophenyl-L-lysine stands out as a valuable asset for both academic and industrial applications.

Synonyms
Fmoc-L-Lys(Dnp)-OH
CAS Number
148083-64-1
Purity
≥ 98% (HPLC)
Molecular Formula
C27H26N4O8
Molecular Weight
534.53
MDL Number
MFCD00273454
PubChem ID
23248982
Melting Point
150 - 160 °C (Lit.)
Appearance
Yellow crystalline powder
Optical Rotation
[a]D20 = -11.5 to -14.0 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Lys(Dnp)-OH
CAS Number
148083-64-1
Purity
≥ 98% (HPLC)
Molecular Formula
C27H26N4O8
Molecular Weight
534.53
MDL Number
MFCD00273454
PubChem ID
23248982
Melting Point
150 - 160 °C (Lit.)
Appearance
Yellow crystalline powder
Optical Rotation
[a]D20 = -11.5 to -14.0 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-2,4-dinitrophenyl-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial for creating complex peptides used in drug development.
  • Bioconjugation: It can be employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules. This is particularly beneficial in creating targeted drug delivery systems in pharmaceuticals.
  • Fluorescent Probes: The dinitrophenyl group can be used to develop fluorescent probes for studying protein interactions and cellular processes, enhancing the understanding of biological mechanisms.
  • Antibody Labeling: This compound is effective in labeling antibodies for immunoassays, improving sensitivity and specificity in detecting target proteins in various research applications.
  • Research in Cancer Therapeutics: Its unique structure allows for the exploration of new cancer therapies by modifying peptides that can selectively target cancer cells, potentially leading to more effective treatments.

Citations