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Catalog Number:
05733
CAS Number:
118584-90-0
N-Fmoc-N-dansyl-L-lysine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Lys(Dansyl)-OH
Documents
$113.87 /100MG
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Product Information

Na-Fmoc-Ne-dansyl-L-lysine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and bioconjugation applications. This compound features a unique combination of a fluorenylmethoxycarbonyl (Fmoc) protecting group and a dansyl moiety, which not only enhances its stability but also provides fluorescent properties. Researchers often utilize Na-Fmoc-Ne-dansyl-L-lysine in the development of fluorescently labeled peptides, enabling the tracking of biological processes in live cells. Its ability to facilitate the synthesis of complex peptides makes it an invaluable tool in drug discovery and development, particularly in the fields of medicinal chemistry and molecular biology.

The compound's distinctive properties allow for easy incorporation into various peptide sequences, making it ideal for applications in targeted drug delivery and biomolecular imaging. Additionally, its fluorescent characteristics enable researchers to visualize and study peptide interactions in real-time, providing insights into cellular mechanisms. Na-Fmoc-Ne-dansyl-L-lysine stands out among similar compounds due to its dual functionality, combining protective and fluorescent features that enhance its utility in both academic and industrial research settings.

Synonyms
Fmoc-L-Lys(Dansyl)-OH
CAS Number
118584-90-0
Purity
≥ 97% (HPLC)
Molecular Formula
C33H35N3O6S
Molecular Weight
601.73
MDL Number
MFCD00672343
PubChem ID
75627319
Appearance
White powder
Optical Rotation
[a]D22 = +9 ± 2º (C=1 in CHCl3)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Lys(Dansyl)-OH
CAS Number
118584-90-0
Purity
≥ 97% (HPLC)
Molecular Formula
C33H35N3O6S
Molecular Weight
601.73
MDL Number
MFCD00672343
PubChem ID
75627319
Appearance
White powder
Optical Rotation
[a]D22 = +9 ± 2º (C=1 in CHCl3)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-dansyl-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is commonly used in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield. Its protective groups facilitate the stepwise addition of amino acids.
  • Fluorescent Labeling: The dansyl group provides excellent fluorescence properties, making it ideal for labeling peptides and proteins in biochemical assays. This enhances detection sensitivity in various applications, including cell imaging.
  • Drug Development: In pharmaceutical research, it serves as a valuable tool for studying drug-receptor interactions, helping to identify potential therapeutic candidates through its ability to mimic natural substrates.
  • Bioconjugation: The compound can be used in bioconjugation techniques, linking biomolecules to surfaces or other molecules. This is particularly useful in creating targeted drug delivery systems or diagnostic tools.
  • Research in Neuroscience: Its fluorescent properties make it suitable for studying neuronal pathways and interactions, providing insights into neurological processes and potential treatments for neurodegenerative diseases.

Citations