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Catalog Number:
03997
CAS Number:
133628-28-1
N-Boc-N-Fmoc-L-lysine methyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Lys(Fmoc)-OMe
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Product Information

Na-Boc-Ne-Fmoc-L-lysine methyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protected lysine residue, making it an essential building block for the creation of complex peptides and proteins. Its unique structure, which includes both Boc and Fmoc protecting groups, allows for selective deprotection under mild conditions, facilitating the synthesis of peptides with high purity and yield. Researchers in the fields of medicinal chemistry and biochemistry often leverage this compound for its ability to enhance solubility and stability of peptides, making it particularly valuable in the development of therapeutic agents.

In addition to its applications in peptide synthesis, Na-Boc-Ne-Fmoc-L-lysine methyl ester is also employed in the design of drug delivery systems and in the formulation of biomaterials. Its compatibility with various coupling reagents and its ability to undergo further modifications make it an attractive choice for researchers looking to innovate in drug design and delivery. The compound's favorable properties, such as its stability and ease of handling, position it as a preferred option for professionals aiming to streamline their research processes and achieve optimal results.

Synonyms
Boc-L-Lys(Fmoc)-OMe
CAS Number
133628-28-1
Purity
≥ 98% (HPLC)
Molecular Formula
C27H34N2O6
Molecular Weight
482.58
MDL Number
MFCD00236856
PubChem ID
76401326
Melting Point
101-108 °C
Optical Rotation
[a]D20 = -9 ± 2º (C=1 in CH3CN)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Lys(Fmoc)-OMe
CAS Number
133628-28-1
Purity
≥ 98% (HPLC)
Molecular Formula
C27H34N2O6
Molecular Weight
482.58
MDL Number
MFCD00236856
PubChem ID
76401326
Melting Point
101-108 °C
Optical Rotation
[a]D20 = -9 ± 2º (C=1 in CH3CN)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Ne-Fmoc-L-lysine methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, facilitating the creation of complex peptide sequences.
  • Drug Development: It is used in the design of peptide-based therapeutics, offering advantages in stability and bioavailability, which are crucial for effective drug formulation.
  • Bioconjugation: The compound is employed in bioconjugation strategies to attach peptides to other biomolecules, enhancing the specificity and efficacy of targeted therapies.
  • Research in Protein Engineering: It plays a role in modifying lysine residues in proteins, allowing researchers to study protein interactions and functions more effectively.
  • Diagnostic Applications: This chemical is also used in the development of diagnostic tools, such as peptide-based assays, which can improve the detection of various diseases.

Citations