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Catalog Number:
03720
CAS Number:
167393-62-6
Nα-Fmoc-Nε-methyltrityl-L-lysine
Purity:
≥ 95% (HPLC)
Synonym(s):
Fmoc-L-Lys(Mtt)-OH
Documents
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Product Information

Na-Fmoc-Ne-methyltrityl-L-lysine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of the amino group during solid-phase peptide synthesis. Its unique structure, which includes a methyltrityl group, enhances stability and solubility, making it an ideal choice for researchers focusing on complex peptide sequences.

In practical applications, Na-Fmoc-Ne-methyltrityl-L-lysine is particularly valuable in the synthesis of bioactive peptides and pharmaceuticals, where precision and purity are paramount. Its ability to facilitate the introduction of lysine residues into peptides allows for the development of therapeutics with improved efficacy and specificity. Additionally, this compound is instrumental in the design of peptide-based drug delivery systems, contributing to advancements in targeted therapies. Researchers and industry professionals will appreciate its reliability and effectiveness in producing high-quality peptides for various applications.

Synonyms
Fmoc-L-Lys(Mtt)-OH
CAS Number
167393-62-6
Purity
≥ 95% (HPLC)
Molecular Formula
C41H40N2O4
Molecular Weight
624.79
MDL Number
MFCD00237166
PubChem ID
67349967
Melting Point
110 - 155 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -10 ± 2 º (C=3 in DMF) [a]D20 = 3 ± 2 º (C=1 in THF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Lys(Mtt)-OH
CAS Number
167393-62-6
Purity
≥ 95% (HPLC)
Molecular Formula
C41H40N2O4
Molecular Weight
624.79
MDL Number
MFCD00237166
PubChem ID
67349967
Melting Point
110 - 155 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -10 ± 2 º (C=3 in DMF) [a]D20 = 3 ± 2 º (C=1 in THF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-methyltrityl-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for amino acids during peptide synthesis, allowing for the selective modification of specific functional groups without affecting others.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, enhancing the stability and efficacy of therapeutic agents.
  • Bioconjugation: The compound facilitates the attachment of peptides to other biomolecules, which is crucial in developing targeted therapies and diagnostics in biotechnology.
  • Protein Engineering: Researchers utilize it to modify lysine residues in proteins, improving their properties for various applications in enzyme engineering and synthetic biology.
  • Research in Cancer Therapy: Its application in creating peptide conjugates has shown promise in targeted cancer therapies, providing a more effective treatment option with reduced side effects.

Citations