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Catalog Number:
02713
CAS Number:
14609-04-2
N-Boc-N-nicotinoyl-L-lysine
Purity:
≥ 97% (HPLC)
Synonym(s):
Boc-L-Lys(nicotinoyl)-OH
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Product Information

Na-Boc-Ne-nicotinoyl-L-lysine is a versatile compound that plays a significant role in peptide synthesis and drug development. This derivative of L-lysine features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and reactivity, making it an ideal choice for researchers engaged in the synthesis of complex peptides. Its unique structure, characterized by the incorporation of a nicotinoyl group, allows for specific interactions in biological systems, which can be leveraged in the design of targeted therapeutics.

This compound is particularly valuable in the fields of medicinal chemistry and biochemistry, where it can be utilized to create peptide-based drugs with improved pharmacological properties. Researchers have found that Na-Boc-Ne-nicotinoyl-L-lysine can facilitate the development of novel drug candidates that target specific receptors, enhancing efficacy while minimizing side effects. Its ability to serve as a building block in the synthesis of bioactive peptides positions it as a crucial tool for scientists aiming to innovate in drug discovery and development.

Synonyms
Boc-L-Lys(nicotinoyl)-OH
CAS Number
14609-04-2
Purity
≥ 97% (HPLC)
Molecular Formula
C17H25N3O5
Molecular Weight
351.4
MDL Number
MFCD00076969
PubChem ID
14836636
Melting Point
131 - 138 °C (Lit.)
Appearance
White solid
Optical Rotation
[a]D20 = -15 ± 2º (C=1% in DMF) (Lit.)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Lys(nicotinoyl)-OH
CAS Number
14609-04-2
Purity
≥ 97% (HPLC)
Molecular Formula
C17H25N3O5
Molecular Weight
351.4
MDL Number
MFCD00076969
PubChem ID
14836636
Melting Point
131 - 138 °C (Lit.)
Appearance
White solid
Optical Rotation
[a]D20 = -15 ± 2º (C=1% in DMF) (Lit.)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Ne-nicotinoyl-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: It plays a role in the design of drug candidates, particularly in creating molecules that can effectively interact with biological targets, enhancing the efficacy of therapeutic agents.
  • Bioconjugation: The compound is used in bioconjugation techniques, where it helps link biomolecules to drugs or imaging agents, improving the targeting and delivery of therapeutics in cancer treatment.
  • Research in Neuroscience: It is valuable in studies related to neurobiology, particularly in exploring the effects of modified lysine residues on neuronal signaling pathways and their implications in neurodegenerative diseases.
  • Protein Engineering: This chemical aids in the modification of proteins to enhance their stability and functionality, which is essential for developing biopharmaceuticals and enzyme-based applications.