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Catalog Number:
00647
CAS Number:
54613-99-9
Nα-Boc-Nε-2-chloro-Z-L-lysine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Lys(2-Cl-Z)-OH
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Product Information

Na-Boc-Ne-2-chloro-Z-L-lysine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a unique structure that includes a chlorophenyl group and two Boc (tert-butyloxycarbonyl) protecting groups, making it an ideal candidate for researchers focused on the synthesis of complex peptides and biologically active molecules. Its ability to protect amino groups during synthesis allows for greater control and efficiency in the formation of peptide bonds, which is essential in the development of pharmaceuticals and therapeutic agents.

In practical applications, Na-Boc-Ne-2-chloro-Z-L-lysine is utilized in the production of peptide-based drugs, particularly those targeting specific biological pathways. Its stability and reactivity make it suitable for various coupling reactions, enabling the creation of tailored peptides for research and therapeutic purposes. Additionally, its unique properties can enhance the solubility and bioavailability of peptide drugs, providing a significant advantage over similar compounds. Researchers and industry professionals can leverage this compound to streamline their synthesis processes and develop innovative solutions in drug discovery and development.

Synonyms
Boc-L-Lys(2-Cl-Z)-OH
CAS Number
54613-99-9
Purity
≥ 98% (HPLC)
Molecular Formula
C19H27ClN2O6
Molecular Weight
414.89
MDL Number
MFCD00038386
PubChem ID
108253
Melting Point
65 - 80 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -12 ± 2 º (C=2 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Lys(2-Cl-Z)-OH
CAS Number
54613-99-9
Purity
≥ 98% (HPLC)
Molecular Formula
C19H27ClN2O6
Molecular Weight
414.89
MDL Number
MFCD00038386
PubChem ID
108253
Melting Point
65 - 80 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -12 ± 2 º (C=2 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Ne-2-chloro-Z-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals. Its protective groups allow for selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Development: It plays a significant role in the creation of novel therapeutic agents. By modifying the lysine residue, researchers can improve the pharmacological properties of drug candidates, leading to more effective treatments.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach drugs or imaging agents to biomolecules. This application is crucial in targeted drug delivery systems, enhancing the specificity and efficacy of treatments.
  • Research in Protein Engineering: It aids in the design of modified proteins with enhanced stability and activity. This is particularly beneficial in the fields of biotechnology and enzyme engineering, where tailored proteins can lead to innovative solutions.
  • Analytical Chemistry: The compound is utilized in analytical methods for studying amino acid sequences and modifications. Its unique structure allows for precise identification and quantification of peptides in complex mixtures.

Citations