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Catalog Number:
05308
CAS Number:
65581-25-1
Z-D-leucine-N-hydroxysuccinimide ester
Purity:
≥ 99%
Synonym(s):
Z-D-Leu-OSu, (R)-Z-2-amino-4-methyl-pentanoic acid N-hydoxysuccinimide ester
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Product Information

Z-D-leucine-N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound serves as a valuable building block in the creation of peptide-based therapeutics, particularly due to its ability to facilitate the formation of peptide bonds with high efficiency. Its unique structure allows for selective reactions, making it an ideal choice for researchers focused on developing novel bioactive peptides. Additionally, the N-hydroxysuccinimide moiety enhances the compound's reactivity, providing a pathway for further functionalization and modification, which is crucial in medicinal chemistry and bioconjugation applications.

In the pharmaceutical industry, Z-D-leucine-N-hydroxysuccinimide ester is particularly beneficial for synthesizing targeted drug delivery systems and improving the stability of peptide drugs. Its application extends to the development of vaccines and therapeutic agents, where precise control over peptide sequences is essential. Researchers appreciate its compatibility with various coupling strategies, making it a preferred choice for those aiming to innovate in peptide design and synthesis. Overall, this compound stands out for its practical applications in advancing peptide chemistry and drug formulation.

Synonyms
Z-D-Leu-OSu, (R)-Z-2-amino-4-methyl-pentanoic acid N-hydoxysuccinimide ester
CAS Number
65581-25-1
Purity
≥ 99%
Molecular Formula
C18H22N2O6
Molecular Weight
362.4
MDL Number
MFCD00153337
PubChem ID
102999
Conditions
Store at 0-8°C
General Information
Synonyms
Z-D-Leu-OSu, (R)-Z-2-amino-4-methyl-pentanoic acid N-hydoxysuccinimide ester
CAS Number
65581-25-1
Purity
≥ 99%
Molecular Formula
C18H22N2O6
Molecular Weight
362.4
MDL Number
MFCD00153337
PubChem ID
102999
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-D-leucine-N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an effective coupling agent in solid-phase peptide synthesis, enhancing the efficiency of forming peptide bonds.
  • Drug Development: It plays a crucial role in the design of peptide-based therapeutics, particularly in improving bioavailability and stability of drug candidates.
  • Bioconjugation: The ester functionality allows for selective conjugation with biomolecules, facilitating the development of targeted drug delivery systems.
  • Diagnostic Applications: It is used in the preparation of peptide probes for various diagnostic assays, aiding in disease detection and monitoring.
  • Research in Proteomics: This compound is valuable in proteomics for labeling and studying protein interactions, contributing to advancements in understanding cellular processes.

Citations