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Catalog Number:
14046
CAS Number:
129672-10-2
Nα-Boc-N-π-benzyloxymethyl-L-histidine N-hydroxysuccinimide ester
Purity:
≥ 98% (TLC)
Synonym(s):
Boc-L-His(p-Bom)-OSu, Boc-His(3-Bom)-OSu
Documents
$43.87 /250MG
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Product Information

Na-Boc-N-p-benzyloxymethyl-L-histidine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a protected histidine residue, which is crucial for the selective modification of peptides and proteins. Its unique structure allows for the introduction of various functional groups, making it an essential tool for researchers in the fields of medicinal chemistry and drug development. The N-hydroxysuccinimide ester functionality enhances its reactivity, facilitating efficient coupling reactions with amines and alcohols, thereby streamlining the synthesis of complex biomolecules.

In addition to its role in peptide synthesis, Na-Boc-N-p-benzyloxymethyl-L-histidine N-hydroxysuccinimide ester is particularly valuable in the development of targeted drug delivery systems and therapeutic agents. Its ability to form stable conjugates with various biomolecules opens up possibilities for creating innovative treatments in cancer therapy and other diseases. Researchers appreciate its ease of use and the high yield of desired products, making it a preferred choice for both academic and industrial applications.

Synonyms
Boc-L-His(p-Bom)-OSu, Boc-His(3-Bom)-OSu
CAS Number
129672-10-2
Purity
≥ 98% (TLC)
Molecular Formula
C23H28N4O7
Molecular Weight
427.5
MDL Number
MFCD00236853
Melting Point
57-83 ?C
Appearance
Off-white product
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-His(p-Bom)-OSu, Boc-His(3-Bom)-OSu
CAS Number
129672-10-2
Purity
≥ 98% (TLC)
Molecular Formula
C23H28N4O7
Molecular Weight
427.5
MDL Number
MFCD00236853
Melting Point
57-83 ?C
Appearance
Off-white product
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-N-p-benzyloxymethyl-L-histidine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key intermediate in the synthesis of peptides, enabling researchers to create complex molecules for various biological studies.
  • Drug Development: It is employed in the development of new pharmaceuticals, particularly in creating targeted drug delivery systems that enhance therapeutic efficacy.
  • Bioconjugation: The compound is useful for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules, facilitating the study of biological interactions.
  • Research in Cancer Therapy: It plays a role in developing novel cancer treatments by modifying drug properties to improve selectivity and reduce side effects.
  • Diagnostics: This chemical is utilized in the design of diagnostic tools, helping to create assays that can detect specific biomolecules in clinical samples.

Citations