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Catalog Number:
06844
CAS Number:
17791-51-4
Nα,Nim-Bis-Boc-L-histidine methyl ester
Purity:
≥ 99%
Synonym(s):
Nα,Nim-bis-Boc-L-histidine methyl ester
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Product Information

Na,Nim-Bis-Boc-L-histidine methyl ester is a versatile compound widely utilized in the fields of biochemistry and pharmaceutical research. This derivative of histidine features a tert-butyl protective group, enhancing its stability and solubility, making it an ideal candidate for peptide synthesis and drug development. Its unique structure allows for selective modifications, which is particularly beneficial in the design of targeted therapies and biologically active compounds. Researchers have effectively employed this compound in the synthesis of peptide-based drugs, where its ability to facilitate the introduction of functional groups can lead to improved bioactivity and specificity.

In addition to its applications in drug development, Na,Nim-Bis-Boc-L-histidine methyl ester serves as a valuable building block in the synthesis of complex biomolecules. Its compatibility with various coupling reactions allows for the efficient assembly of peptide chains, which are crucial in the development of vaccines and therapeutic proteins. The compound's favorable properties, such as its stability under physiological conditions, make it an essential tool for researchers aiming to innovate in the fields of medicinal chemistry and biotechnology.

Synonyms
Nα,Nim-bis-Boc-L-histidine methyl ester
CAS Number
17791-51-4
Purity
≥ 99%
Molecular Formula
C17H27N3O6
Molecular Weight
369.42
MDL Number
MFCD03094049
PubChem ID
4101101
Appearance
White to off-white solid
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Nα,Nim-bis-Boc-L-histidine methyl ester
CAS Number
17791-51-4
Purity
≥ 99%
Molecular Formula
C17H27N3O6
Molecular Weight
369.42
MDL Number
MFCD03094049
PubChem ID
4101101
Appearance
White to off-white solid
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na,Nim-Bis-Boc-L-histidine methyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutics. Its stable structure allows for efficient coupling reactions, making it a preferred choice for researchers.
  • Drug Development: In pharmaceutical research, it is used to create histidine-containing compounds that can enhance drug efficacy. Its ability to modify drug properties makes it valuable in optimizing formulations.
  • Bioconjugation: The compound is utilized in bioconjugation processes, where it helps link biomolecules to therapeutic agents. This application is crucial in creating targeted delivery systems for cancer therapies.
  • Protein Engineering: Researchers use it to modify proteins, improving their stability and activity. This is particularly beneficial in the development of enzymes and antibodies for various applications.
  • Research in Biochemistry: Its role in studying histidine's function in biological systems is significant, aiding in understanding metabolic pathways and enzyme mechanisms.

Citations