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Catalog Number:
05496
CAS Number:
204125-02-0(net)
Nα-Boc-Nim-2,4-dinitrophenyl-D-histidine·isopropanol
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-D-His(Dnp)-OH·IPA
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Product Information

Na-Boc-Nim-2,4-dinitrophenyl-D-histidine·isopropanol is a specialized chemical compound that serves as a valuable tool in biochemical research and pharmaceutical development. This compound, also known as Boc-D-His(DNP)-OH, is particularly significant for its role in peptide synthesis and modification, allowing researchers to explore various biological interactions and therapeutic potentials. Its unique structure, featuring a dinitrophenyl group, enhances its reactivity and provides a means for selective labeling in biological assays, making it an essential component in the study of protein interactions and enzyme activity.

The compound's solubility in isopropanol further facilitates its use in various laboratory settings, enabling easy handling and incorporation into complex reactions. Researchers in the fields of medicinal chemistry and biochemistry can leverage Na-Boc-Nim-2,4-dinitrophenyl-D-histidine·isopropanol for the development of novel drug candidates, particularly in the design of targeted therapies. Its ability to modify histidine residues in peptides opens avenues for creating more effective and selective therapeutic agents, enhancing the overall efficacy of drug formulations.

Synonyms
Boc-D-His(Dnp)-OH·IPA
CAS Number
204125-02-0(net)
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C17H19N5O8·C3H8O
Molecular Weight
481.5
MDL Number
MFCD00672320
PubChem ID
13825421
Melting Point
110 - 113 ?C
Appearance
Light yellow powder
Optical Rotation
[a]20D = -65 ± 1 ° (C=1 in EtOAC)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-D-His(Dnp)-OH·IPA
CAS Number
204125-02-0(net)
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C17H19N5O8·C3H8O
Molecular Weight
481.5
MDL Number
MFCD00672320
PubChem ID
13825421
Melting Point
110 - 113 ?C
Appearance
Light yellow powder
Optical Rotation
[a]20D = -65 ± 1 ° (C=1 in EtOAC)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nim-2,4-dinitrophenyl-D-histidine·isopropanol is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting the overall structure. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its unique structure aids in the design of novel drug candidates, particularly in targeting specific biological pathways. Researchers can modify the compound to enhance efficacy and reduce side effects.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach drugs or labels to biomolecules. This is particularly beneficial in creating targeted therapies and diagnostic agents in cancer treatment.
  • Analytical Chemistry: It plays a role in analytical methods, such as chromatography and mass spectrometry, helping to identify and quantify biomolecules in complex mixtures, which is essential for quality control in pharmaceuticals.
  • Research in Immunology: The compound is utilized in the development of immunoassays, aiding in the detection of specific antibodies or antigens, which is vital for vaccine development and disease diagnosis.

Citations