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Catalog Number:
05304
CAS Number:
20898-44-6
Nα-Boc-Nim-benzyl-L-histidine
Purity:
≥ 98% (TLC)
Synonym(s):
Boc-L-His(Bzl)-OH
Documents
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Product Information

Na-Boc-Nim-benzyl-L-histidine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a unique Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry. Its structural characteristics allow for easy incorporation into peptides, facilitating the exploration of novel therapeutic agents.

With applications spanning from the development of enzyme inhibitors to the synthesis of complex biomolecules, Na-Boc-Nim-benzyl-L-histidine is particularly valuable in the pharmaceutical industry. Its ability to mimic natural amino acids while providing additional functional groups opens avenues for creating more effective drugs with improved bioavailability. Researchers can leverage this compound to optimize lead compounds and enhance their pharmacological profiles, making it a key player in the quest for innovative treatments.

Synonyms
Boc-L-His(Bzl)-OH
CAS Number
20898-44-6
Purity
≥ 98% (TLC)
Molecular Formula
C18H23N3O4
Molecular Weight
345.4
MDL Number
MFCD00066093
PubChem ID
89402
Melting Point
178-187? C
Appearance
White to off-white powder
Optical Rotation
+23.0 ± 1º (c=1, in MeOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-His(Bzl)-OH
CAS Number
20898-44-6
Purity
≥ 98% (TLC)
Molecular Formula
C18H23N3O4
Molecular Weight
345.4
MDL Number
MFCD00066093
PubChem ID
89402
Melting Point
178-187? C
Appearance
White to off-white powder
Optical Rotation
+23.0 ± 1º (c=1, in MeOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nim-benzyl-L-histidine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of biologically active compounds and pharmaceuticals.
  • Drug Development: Its unique structure allows for modifications that can enhance the efficacy and selectivity of drug candidates, making it valuable in medicinal chemistry.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to therapeutic agents, improving targeted delivery in cancer therapies.
  • Research in Enzyme Inhibition: It plays a role in studies aimed at understanding enzyme mechanisms, particularly in the context of designing inhibitors for various diseases.
  • Protein Engineering: The compound is instrumental in protein engineering applications, providing researchers with tools to modify protein properties for enhanced stability and activity.

Citations