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Catalog Number:
03921
CAS Number:
84891-19-0
Fmoc-His(3-Bom)-OH
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-His(π-Bom)-OH, Fmoc-N-p-benzyloxymethyl-L-histidine
Documents
$72.31 /1G
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Product Information

Fmoc-His(3-Bom)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of the amino group during the synthesis of peptides. Its unique structure, incorporating a 3-benzyl-oxy-methyl imidazole side chain, enhances its stability and reactivity, making it an excellent choice for researchers focused on developing complex peptide sequences.

In the pharmaceutical and biotechnology industries, Fmoc-His(3-Bom)-OH is particularly valuable for the synthesis of histidine-containing peptides, which are crucial for various biological functions and therapeutic applications. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups allows for the efficient production of high-purity peptides. Researchers can leverage this compound to create innovative drug candidates, diagnostic tools, and therapeutic agents, thereby advancing their projects with greater efficiency and precision.

Synonyms
Fmoc-L-His(π-Bom)-OH, Fmoc-N-p-benzyloxymethyl-L-histidine
CAS Number
84891-19-0
Purity
≥ 99% (HPLC)
Molecular Formula
C29H27N3O5
Molecular Weight
497.56
MDL Number
MFCD00077059
PubChem ID
4637432
Appearance
White powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-His(π-Bom)-OH, Fmoc-N-p-benzyloxymethyl-L-histidine
CAS Number
84891-19-0
Purity
≥ 99% (HPLC)
Molecular Formula
C29H27N3O5
Molecular Weight
497.56
MDL Number
MFCD00077059
PubChem ID
4637432
Appearance
White powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-His(3-Bom)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly those containing histidine. Its protective Fmoc group allows for selective deprotection during the synthesis process, enhancing efficiency and yield.
  • Drug Development: In pharmaceutical research, it is used to create histidine-containing peptides that can act as potential drug candidates, especially in targeting specific biological pathways or diseases.
  • Bioconjugation: The compound facilitates the attachment of biomolecules, such as proteins or antibodies, to therapeutic agents, improving their efficacy and targeting capabilities in treatments like cancer therapy.
  • Research in Biochemistry: It is employed in studies investigating enzyme activity and protein interactions, providing insights into metabolic pathways and cellular functions.
  • Diagnostics: The compound can be utilized in the development of diagnostic tools, particularly in assays that require histidine for binding or detection purposes, enhancing the sensitivity and specificity of tests.

Citations