Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
03008
CAS Number:
50305-43-6
Boc-His(Z)-OH
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-Nim-Z-L-histidine
Documents
$43.87 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Na-Boc-Nim-Z-L-histidine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers in the fields of biochemistry and medicinal chemistry. Its unique structure allows for selective reactions, facilitating the formation of complex peptides that can be utilized in various therapeutic applications, including cancer treatment and vaccine development.

In addition to its applications in peptide synthesis, Na-Boc-Nim-Z-L-histidine is also valuable in the study of enzyme mechanisms and protein interactions. Its ability to mimic natural amino acids while providing additional functional groups makes it a powerful tool for designing novel biomolecules. Researchers can leverage this compound to explore new pathways in drug discovery and development, ultimately contributing to advancements in pharmaceutical sciences.

Synonyms
Boc-Nim-Z-L-histidine
CAS Number
50305-43-6
Purity
≥ 99% (HPLC)
Molecular Formula
C19H23N3O6
Molecular Weight
389.41
MDL Number
MFCD00076942
PubChem ID
13712212
Melting Point
110-116 ?C
Appearance
White powder
Optical Rotation
[a]D20 = +3.4 ± 0.5º (C=1 in DMF)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Boc-Nim-Z-L-histidine
CAS Number
50305-43-6
Purity
≥ 99% (HPLC)
Molecular Formula
C19H23N3O6
Molecular Weight
389.41
MDL Number
MFCD00076942
PubChem ID
13712212
Melting Point
110-116 ?C
Appearance
White powder
Optical Rotation
[a]D20 = +3.4 ± 0.5º (C=1 in DMF)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nim-Z-L-histidine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for selective reactions and improving yield. Its stability under various conditions makes it a preferred choice for researchers in organic chemistry.
  • Drug Development: In pharmaceutical research, it is used to create histidine derivatives that can enhance drug efficacy. By modifying histidine, researchers can develop new therapeutic agents targeting specific diseases.
  • Bioconjugation: The compound is valuable in bioconjugation processes, where it aids in attaching biomolecules to surfaces or other molecules. This application is crucial in developing targeted drug delivery systems.
  • Protein Engineering: It plays a significant role in protein engineering, where it is used to modify histidine residues in proteins, improving their stability and functionality for various applications in biotechnology.
  • Research in Catalysis: The compound is also explored in catalytic processes, particularly in asymmetric synthesis. Its unique structure can facilitate reactions that are essential in creating complex organic molecules.

Citations