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Catalog Number:
03792
CAS Number:
3655-05-8
Boc-glycine 4-nitrophenyl ester
Purity:
≥ 98% (TLC)
Synonym(s):
Boc-Gly-ONp
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Product Information

Boc-glycine 4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This compound features a protective Boc (tert-butyloxycarbonyl) group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its 4-nitrophenyl ester moiety enhances its reactivity, making it an excellent choice for coupling reactions. Researchers and industry professionals appreciate its ability to facilitate the formation of peptide bonds, thus streamlining the synthesis of complex peptides and proteins.

In addition to its role in peptide synthesis, Boc-glycine 4-nitrophenyl ester is also employed in the development of pharmaceutical intermediates, where its unique structure allows for the introduction of functional groups that can be further modified. Its stability and ease of handling make it a preferred choice in laboratories focused on drug discovery and development. This compound not only enhances the efficiency of synthetic processes but also opens avenues for innovative research in biochemistry and pharmacology.

Synonyms
Boc-Gly-ONp
CAS Number
3655-05-8
Purity
≥ 98% (TLC)
Molecular Formula
C13H16N2O6
Molecular Weight
296.3
MDL Number
MFCD00038125
PubChem ID
77217
Melting Point
56-66 °C
Appearance
Brown powder
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-Gly-ONp
CAS Number
3655-05-8
Purity
≥ 98% (TLC)
Molecular Formula
C13H16N2O6
Molecular Weight
296.3
MDL Number
MFCD00038125
PubChem ID
77217
Melting Point
56-66 °C
Appearance
Brown powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-glycine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for selective reactions without affecting other functional groups. Its use simplifies the process of building complex peptide chains.
  • Drug Development: In medicinal chemistry, it acts as an intermediate in the development of pharmaceutical compounds, particularly those targeting specific biological pathways. This can lead to more effective drugs with fewer side effects.
  • Bioconjugation: The compound is valuable in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic tools and therapeutic agents.
  • Research in Enzyme Inhibition: It is utilized in studies aimed at understanding enzyme mechanisms, particularly in the design of enzyme inhibitors that can lead to new treatments for diseases.
  • Analytical Chemistry: Boc-glycine 4-nitrophenyl ester is used as a reagent in various analytical methods, aiding in the detection and quantification of amino acids and peptides in complex mixtures.

Citations