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Catalog Number:
02420
CAS Number:
113484-74-5
Fmoc-glycine N-hydroxysuccinimide ester
Purity:
≥ 95% (HPLC)
Synonym(s):
Fmoc-Gly-OSu
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Product Information

Fmoc-glycine N-hydroxysuccinimide ester is a versatile and valuable compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is essential for the selective protection of amino groups during peptide assembly. Its N-hydroxysuccinimide ester functionality enhances its reactivity, making it an ideal choice for coupling reactions with various nucleophiles, including amines and alcohols. Researchers and industry professionals appreciate its ability to facilitate the formation of stable amide bonds, which is crucial in the development of peptide-based therapeutics and biomaterials.

In addition to its applications in peptide synthesis, Fmoc-glycine N-hydroxysuccinimide ester is also employed in the preparation of functionalized surfaces and drug delivery systems. Its unique properties allow for efficient conjugation to biomolecules, enabling the design of targeted therapies and diagnostic tools. With its high purity and reliability, this compound stands out as a preferred choice for researchers looking to streamline their synthesis processes and enhance the efficacy of their products.

Synonyms
Fmoc-Gly-OSu
CAS Number
113484-74-5
Purity
≥ 95% (HPLC)
Molecular Formula
C21H18N2O6
Molecular Weight
394.4
MDL Number
MFCD00065651
Melting Point
168-175 ºC
Appearance
White to off-white powder
Conditions
Store at ≤ - 4 °C
General Information
Synonyms
Fmoc-Gly-OSu
CAS Number
113484-74-5
Purity
≥ 95% (HPLC)
Molecular Formula
C21H18N2O6
Molecular Weight
394.4
MDL Number
MFCD00065651
Melting Point
168-175 ºC
Appearance
White to off-white powder
Conditions
Store at ≤ - 4 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-glycine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of glycine residues in a controlled manner. Its stability and ease of use make it a preferred choice among chemists.
  • Drug Development: It plays a significant role in the development of peptide-based therapeutics. Researchers can modify the structure to enhance bioactivity, leading to more effective drug candidates.
  • Bioconjugation: The N-hydroxysuccinimide group facilitates efficient coupling reactions with various biomolecules, making it invaluable for creating targeted drug delivery systems and diagnostic agents.
  • Protein Labeling: This ester can be used for labeling proteins with fluorescent tags, aiding in the study of protein interactions and dynamics in biological systems.
  • Research in Neuroscience: Its application in synthesizing neuropeptides allows researchers to explore neurological pathways and develop potential treatments for neurological disorders.

Citations