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Catalog Number:
00032
CAS Number:
150-25-4
Bicine
Purity:
98 - 101% (Assay by titration)
Synonym(s):
N,N-Bis(2-hydroxyethyl)glycine, Diethanolglycine
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$19.73 /25G
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Product Information

Bicine is a versatile zwitterionic buffer widely utilized in biochemical and molecular biology applications. With its unique structure, Bicine offers excellent buffering capacity in the physiological pH range, making it ideal for use in enzyme assays, protein purification, and electrophoresis. Its low ionic strength and minimal interference with biological systems enhance its suitability for sensitive applications, such as cell culture and DNA/RNA studies. Researchers appreciate Bicine for its stability and compatibility with various biological molecules, which allows for reliable results in experiments.

In addition to its role as a buffer, Bicine is also employed in the formulation of various pharmaceutical products and diagnostic kits, where maintaining a stable pH is crucial. Its ability to maintain consistent conditions under varying temperatures and concentrations makes it a preferred choice over other buffering agents. Bicine's applications extend to the food industry as well, where it can be used to stabilize pH in food products. Overall, Bicine stands out for its effectiveness and reliability, making it an essential compound for researchers and industry professionals alike.

Synonyms
N,N-Bis(2-hydroxyethyl)glycine, Diethanolglycine
CAS Number
150-25-4
Purity
98 - 101% (Assay by titration)
Molecular Formula
C6H13NO4
Molecular Weight
163.2
MDL Number
MFCD00004295
PubChem ID
8761
Melting Point
190 °C (dec.)
Appearance
White crystalline powder
Conditions
Store at RT
General Information
Synonyms
N,N-Bis(2-hydroxyethyl)glycine, Diethanolglycine
CAS Number
150-25-4
Purity
98 - 101% (Assay by titration)
Molecular Formula
C6H13NO4
Molecular Weight
163.2
MDL Number
MFCD00004295
PubChem ID
8761
Melting Point
190 °C (dec.)
Appearance
White crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Bicine is widely utilized in research focused on:

  • Biochemical Research: Bicine serves as a buffering agent in various biochemical assays, helping to maintain pH stability during experiments, which is crucial for enzyme activity and protein stability.
  • Electrophoresis: It is commonly used in gel electrophoresis, particularly for separating proteins and nucleic acids, due to its low ionic strength and minimal interference with biological samples.
  • Pharmaceutical Development: In drug formulation, Bicine acts as a stabilizer for active pharmaceutical ingredients, enhancing solubility and bioavailability, which is vital for effective medication delivery.
  • Cell Culture: This compound is employed in cell culture media, providing a suitable environment for cell growth and maintenance, thus supporting research in cellular biology and biotechnology.
  • Diagnostics: Bicine is used in diagnostic kits for various assays, where its buffering capacity ensures accurate and reliable results, making it essential in clinical laboratories.

Citations