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Catalog Number:
03614
CAS Number:
120658-64-2
Nα-Fmoc-Nδ-2,4,6-trimethoxybenzyl-L-glutamine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Gln(Tmob)-OH
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$120.88 /1G
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Product Information

Na-Fmoc-Nd-2,4,6-trimethoxybenzyl-L-glutamine is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which enhances its stability and solubility, making it an ideal choice for solid-phase peptide synthesis. Its unique structure allows for the incorporation of the trimethoxybenzyl group, which can significantly influence the biological activity and pharmacokinetics of the resulting peptides. Researchers and industry professionals appreciate this compound for its ability to facilitate the synthesis of complex peptides with improved efficacy in therapeutic applications, particularly in the fields of oncology and immunology.

The compound's properties make it particularly valuable in the development of peptide-based drugs, where the precise control of amino acid sequences is critical. Its effectiveness in enhancing peptide stability and bioavailability positions it as a preferred choice for those engaged in cutting-edge pharmaceutical research. With its robust profile, Na-Fmoc-Nd-2,4,6-trimethoxybenzyl-L-glutamine stands out as a key reagent for advancing peptide chemistry and therapeutic innovation.

Synonyms
Fmoc-L-Gln(Tmob)-OH
CAS Number
120658-64-2
Purity
≥ 99% (HPLC)
Molecular Formula
C30H32N2O8
Molecular Weight
548.6
MDL Number
MFCD00153355
PubChem ID
5086629
Melting Point
166 - 168 ?C
Appearance
White powder
Optical Rotation
[a]D24 = 22 ± 1 ° (C=1% in Chloroform)
Conditions
Store at RT
General Information
Synonyms
Fmoc-L-Gln(Tmob)-OH
CAS Number
120658-64-2
Purity
≥ 99% (HPLC)
Molecular Formula
C30H32N2O8
Molecular Weight
548.6
MDL Number
MFCD00153355
PubChem ID
5086629
Melting Point
166 - 168 ?C
Appearance
White powder
Optical Rotation
[a]D24 = 22 ± 1 ° (C=1% in Chloroform)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nd-2,4,6-trimethoxybenzyl-L-glutamine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in peptide synthesis, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, enhancing the bioavailability and efficacy of therapeutic agents.
  • Bioconjugation: The compound facilitates the attachment of biomolecules, such as proteins or antibodies, to drug carriers, improving targeted delivery systems in cancer therapy.
  • Analytical Chemistry: It is employed in chromatography and mass spectrometry to analyze complex mixtures, providing clearer insights into molecular structures and interactions.
  • Research in Neuroscience: The compound is utilized in studies involving neurotransmitter pathways, aiding in the understanding of neurological disorders and the development of potential treatments.

Citations