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Catalog Number:
26456
CAS Number:
292150-20-0
Fmoc-D-glutamic acid α-amide
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Glu-NH2, Fmoc-D-Igln-OH
Documents
$93.14 /250MG
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Product Information

Fmoc-D-glutamic acid a-amide is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential tool for chemists working on complex peptide sequences. Its unique structure not only enhances solubility but also improves stability, which is crucial for maintaining the integrity of sensitive compounds during synthesis.

Researchers and industry professionals can leverage Fmoc-D-glutamic acid a-amide in various applications, including the development of peptide-based therapeutics and the synthesis of bioactive compounds. Its ability to facilitate the incorporation of glutamic acid into peptides makes it particularly valuable in the design of neuropeptides and other biologically active molecules. With its favorable properties and practical applications, this compound stands out as a key ingredient for advancing research in medicinal chemistry and biochemistry.

Synonyms
Fmoc-D-Glu-NH2, Fmoc-D-Igln-OH
CAS Number
292150-20-0
Purity
≥ 98% (HPLC)
Molecular Formula
C20H20N2O5
Molecular Weight
368.39
MDL Number
MFCD01861343
PubChem ID
10090419
Melting Point
197 - 201 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -7 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Glu-NH2, Fmoc-D-Igln-OH
CAS Number
292150-20-0
Purity
≥ 98% (HPLC)
Molecular Formula
C20H20N2O5
Molecular Weight
368.39
MDL Number
MFCD01861343
PubChem ID
10090419
Melting Point
197 - 201 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -7 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-glutamic acid a-amide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing peptide-based drugs, enhancing the stability and bioavailability of therapeutic agents.
  • Bioconjugation: Researchers use it for bioconjugation processes, linking peptides to other biomolecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: The compound is valuable in studying neurotransmitter functions and developing neuroprotective agents, contributing to advancements in treating neurological disorders.
  • Protein Engineering: It is employed in the modification of proteins to improve their properties, such as solubility and stability, which is vital in various biotechnological applications.

Citations