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Catalog Number:
11184
CAS Number:
104091-11-4
Fmoc-D-glutamic acid े-benzyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-glutamic acid Γ-benzyl ester, Fmoc-D-glutamic acid 5-benzyl ester
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Product Information

Fmoc-D-glutamic acid g-benzyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure not only enhances the stability of the amino acid but also facilitates the formation of complex peptide sequences, making it an invaluable tool for researchers in the fields of medicinal chemistry and biochemistry.

In practical applications, Fmoc-D-glutamic acid g-benzyl ester is particularly beneficial in the synthesis of bioactive peptides and pharmaceuticals, where precise control over amino acid sequences is crucial. Its ability to undergo smooth deprotection under mild conditions allows for the efficient assembly of peptides without compromising their integrity. This compound is also recognized for its potential in developing targeted therapies and novel drug candidates, providing researchers with a reliable building block for innovative solutions in therapeutic applications.

Synonyms
Fmoc-D-glutamic acid Γ-benzyl ester, Fmoc-D-glutamic acid 5-benzyl ester
CAS Number
104091-11-4
Purity
≥ 99% (HPLC)
Molecular Formula
C27H25NO6
Molecular Weight
459.5
MDL Number
MFCD00273449
PubChem ID
4217184
Melting Point
147 - 152 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20D = -11 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-glutamic acid Γ-benzyl ester, Fmoc-D-glutamic acid 5-benzyl ester
CAS Number
104091-11-4
Purity
≥ 99% (HPLC)
Molecular Formula
C27H25NO6
Molecular Weight
459.5
MDL Number
MFCD00273449
PubChem ID
4217184
Melting Point
147 - 152 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20D = -11 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-glutamic acid g-benzyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing researchers to selectively modify amino acids without affecting others. Its stability under various conditions makes it a preferred choice in complex peptide assembly.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, particularly in targeting specific receptors. Its unique structure aids in enhancing the bioavailability of therapeutic peptides.
  • Bioconjugation: This chemical is applied in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules. This is crucial in developing diagnostic tools and targeted drug delivery systems.
  • Protein Engineering: Researchers utilize this compound in modifying proteins to study their functions and interactions. Its ability to form stable conjugates is beneficial in understanding protein dynamics.
  • Material Science: In the field of materials, it is used to create functionalized polymers that can be employed in drug delivery systems or as scaffolds in tissue engineering, providing enhanced performance over traditional materials.

Citations