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Catalog Number:
05715
CAS Number:
121343-82-6
Fmoc-L-glutamic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Glu-OH
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Product Information

Fmoc-L-glutamic acid is a versatile amino acid derivative widely utilized in peptide synthesis and research applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protective group, which enhances its stability and solubility, making it an ideal choice for solid-phase peptide synthesis. Researchers appreciate its role in facilitating the formation of complex peptides, particularly in the development of pharmaceuticals and bioconjugates. The Fmoc group allows for easy removal under mild conditions, ensuring that the integrity of sensitive functional groups is maintained throughout the synthesis process.

In addition to its applications in peptide synthesis, Fmoc-L-glutamic acid is also valuable in the study of protein interactions and enzyme activity. Its unique properties enable researchers to explore various biochemical pathways and develop targeted therapies. With its proven efficacy and reliability, Fmoc-L-glutamic acid stands out as a preferred choice for professionals in the fields of biochemistry, molecular biology, and pharmaceutical development, offering a robust solution for advancing research and innovation.

Synonyms
Fmoc-L-Glu-OH
CAS Number
121343-82-6
Purity
≥ 98% (HPLC)
Molecular Formula
C20H19NO6
Molecular Weight
369.38
MDL Number
MFCD00237657
PubChem ID
4389144
Melting Point
188-194 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -20 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Glu-OH
CAS Number
121343-82-6
Purity
≥ 98% (HPLC)
Molecular Formula
C20H19NO6
Molecular Weight
369.38
MDL Number
MFCD00237657
PubChem ID
4389144
Melting Point
188-194 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -20 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective coupling of amino acids while preventing unwanted reactions.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, enhancing the stability and bioavailability of therapeutic compounds.
  • Bioconjugation: Fmoc-L-glutamic acid is employed in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in developing biosensors.
  • Protein Engineering: Researchers utilize it in the modification of proteins, enabling the introduction of specific functionalities that can improve protein performance in various applications.
  • Research in Neuroscience: It is also significant in studying neurotransmitter pathways, as glutamic acid is a key neurotransmitter, helping researchers understand brain functions and disorders.

Citations