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Catalog Number:
05493
CAS Number:
73872-71-6
Boc-D-glutamic acid ॅ-tert-butyl ester
Purity:
≥ 98% (NMR)
Synonym(s):
Boc-D-Glu-OtBu
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Product Information

Boc-D-glutamic acid a-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected amino acid derivative features a tert-butyl ester group, which enhances its stability and solubility, making it an ideal choice for various applications in organic synthesis. Researchers often leverage its unique properties to facilitate the formation of peptide bonds, allowing for the efficient construction of complex peptide structures. Its protective Boc (tert-butyloxycarbonyl) group also provides a convenient means of controlling reactivity during multi-step synthesis processes, ensuring high yields and purity.

In the pharmaceutical industry, Boc-D-glutamic acid a-tert-butyl ester serves as a crucial building block for the development of bioactive peptides and drug candidates. Its ability to mimic natural amino acids while providing enhanced stability makes it particularly valuable in the design of therapeutics targeting specific biological pathways. Additionally, its applications extend to the fields of biochemistry and molecular biology, where it is employed in the synthesis of peptide-based probes and inhibitors. With its robust profile and practical applications, this compound is an essential tool for researchers and industry professionals alike.

Synonyms
Boc-D-Glu-OtBu
CAS Number
73872-71-6
Purity
≥ 98% (NMR)
Molecular Formula
C14H25NO6
Molecular Weight
303.36
MDL Number
MFCD00076926
PubChem ID
295484
Appearance
White powder
Optical Rotation
[a]D20 = +31.0 ± 2º (C=1.0, in MeOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-D-Glu-OtBu
CAS Number
73872-71-6
Purity
≥ 98% (NMR)
Molecular Formula
C14H25NO6
Molecular Weight
303.36
MDL Number
MFCD00076926
PubChem ID
295484
Appearance
White powder
Optical Rotation
[a]D20 = +31.0 ± 2º (C=1.0, in MeOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-glutamic acid a-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions while preventing unwanted side reactions. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, it is used to create prodrugs that enhance the bioavailability of active pharmaceutical ingredients. This can lead to more effective medications with fewer side effects.
  • Bioconjugation: The compound is instrumental in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Research in Neuroscience: It is used in the synthesis of glutamate analogs, which are crucial for studying neurotransmitter functions and developing treatments for neurological disorders.
  • Material Science: The compound finds applications in the development of polymers and materials that require specific functional groups, enhancing properties like solubility and stability in various environments.

Citations