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Catalog Number:
05488
CAS Number:
104719-63-3
Boc-D-glutamic acid-े-tert-butyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-D-Glu(OtBu)-OH, Boc-D-glutamic acid 5-tert-butyl ester
Documents
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Product Information

Boc-D-glutamic acid-g-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected amino acid derivative features a tert-butyl ester group, which enhances its stability and solubility, making it an ideal choice for various applications in organic synthesis. Researchers often employ Boc-D-glutamic acid-g-tert-butyl ester in the development of bioactive peptides, where its protective groups facilitate selective reactions and improve yields. Its unique structure allows for easy incorporation into peptide chains, enabling the design of complex molecules with specific biological activities.

In addition to its role in peptide synthesis, Boc-D-glutamic acid-g-tert-butyl ester is also valuable in the field of medicinal chemistry, where it serves as a building block for drug development. Its ability to form stable linkages and its compatibility with various coupling reagents make it a preferred choice for chemists aiming to create novel therapeutic agents. With its favorable properties and broad applicability, Boc-D-glutamic acid-g-tert-butyl ester stands out as an essential tool for researchers and industry professionals focused on advancing peptide-based therapeutics.

Synonyms
Boc-D-Glu(OtBu)-OH, Boc-D-glutamic acid 5-tert-butyl ester
CAS Number
104719-63-3
Purity
≥ 99% (HPLC)
Molecular Formula
C14H25NO6
Molecular Weight
303.4
MDL Number
MFCD00076927
PubChem ID
294901
Melting Point
106 - 109 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 5 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-D-Glu(OtBu)-OH, Boc-D-glutamic acid 5-tert-butyl ester
CAS Number
104719-63-3
Purity
≥ 99% (HPLC)
Molecular Formula
C14H25NO6
Molecular Weight
303.4
MDL Number
MFCD00076927
PubChem ID
294901
Melting Point
106 - 109 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 5 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-glutamic acid-g-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It is used in the design of pharmaceutical compounds, particularly in creating prodrugs that enhance bioavailability and target specificity.
  • Biotechnology: In the field of biotechnology, it aids in the development of bioconjugates, which are essential for targeted drug delivery systems.
  • Research in Neuroscience: The compound is valuable in studying neurotransmitter pathways, as it can mimic natural amino acids and help in the exploration of their roles in the brain.
  • Analytical Chemistry: It is employed in various analytical techniques to improve the separation and identification of complex mixtures, enhancing the accuracy of results.

Citations