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Catalog Number:
05078
CAS Number:
104090-92-8
Fmoc-L-glutamic acid े-tert-butyl ester ॅ-amide
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Glu(OtBu)-NH2, Fmoc-L-isoglutamine t-butyl ester
Documents
$58.39 /1G
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Product Information

Fmoc-L-glutamic acid g-tert-butyl ester a-amide is a versatile compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides excellent stability during the synthesis process, allowing for selective deprotection under mild conditions. Its unique structure enhances solubility and reactivity, making it an ideal choice for researchers working on complex peptide sequences or in the development of pharmaceutical compounds.

In addition to its role in peptide synthesis, Fmoc-L-glutamic acid g-tert-butyl ester a-amide is also valuable in the production of bioactive molecules and can serve as a building block for various applications in medicinal chemistry. Its ability to facilitate the incorporation of glutamic acid into peptides allows for the exploration of novel therapeutic agents, particularly in the fields of oncology and neurology. Researchers appreciate its reliability and efficiency, making it a preferred choice for those aiming to streamline their synthetic pathways while maintaining high yields and purity.

Synonyms
Fmoc-L-Glu(OtBu)-NH2, Fmoc-L-isoglutamine t-butyl ester
CAS Number
104090-92-8
Purity
≥ 99% (HPLC)
Molecular Formula
C24H28N2O5
Molecular Weight
424.5
MDL Number
MFCD01632029
PubChem ID
15407491
Melting Point
150-156 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +4 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Glu(OtBu)-NH2, Fmoc-L-isoglutamine t-butyl ester
CAS Number
104090-92-8
Purity
≥ 99% (HPLC)
Molecular Formula
C24H28N2O5
Molecular Weight
424.5
MDL Number
MFCD01632029
PubChem ID
15407491
Melting Point
150-156 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +4 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid g-tert-butyl ester a-amide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, due to its protective Fmoc group that allows for selective deprotection.
  • Drug Development: It is used in the development of pharmaceuticals, especially in creating drug candidates that target specific biological pathways, enhancing efficacy and reducing side effects.
  • Bioconjugation: The compound is valuable in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other compounds, which is crucial in creating targeted drug delivery systems.
  • Research in Neuroscience: Its derivatives are often explored in neuroscience research to study neurotransmitter pathways, particularly in understanding the role of glutamate in synaptic transmission.
  • Protein Engineering: This chemical is applied in protein engineering to modify protein structures, improving their stability and functionality for various applications in biotechnology.

Citations