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Catalog Number:
04980
CAS Number:
193475-66-0
Fmoc-L-glutamic acid े-[ॆ-(5-naphthyl sulfonic acid)-ethylenediamine] ester
Purity:
≥ 96% (HPLC)
Synonym(s):
Fmoc-L-Glu(Edans)-OH
Documents
$95.60 /100MG
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Product Information

Fmoc-L-glutamic acid g-[b-(5-naphthyl sulfonic acid)-ethylenediamine] ester is a specialized derivative of glutamic acid, widely recognized for its applications in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethyloxycarbonyl) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its structure incorporates a naphthyl sulfonic acid moiety, enhancing its solubility and reactivity, making it particularly valuable in the synthesis of complex peptides and proteins.

Researchers and industry professionals utilize this compound for its ability to facilitate the formation of peptide bonds while maintaining stability under various conditions. Its unique properties allow for improved yields and purity in peptide synthesis, making it an ideal choice for pharmaceutical applications, including the development of therapeutic peptides and biologically active compounds. Additionally, the compound's compatibility with various coupling reagents and its ease of removal of the Fmoc group further enhance its utility in laboratory settings.

Synonyms
Fmoc-L-Glu(Edans)-OH
CAS Number
193475-66-0
Purity
≥ 96% (HPLC)
Molecular Formula
C32H31N3O8S
Molecular Weight
617.68
MDL Number
MFCD01076138
PubChem ID
3641061
Melting Point
215 - 231 °C
Appearance
Gray or off-white powder
Optical Rotation
[a]20D = -2.7 to -4.7 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Glu(Edans)-OH
CAS Number
193475-66-0
Purity
≥ 96% (HPLC)
Molecular Formula
C32H31N3O8S
Molecular Weight
617.68
MDL Number
MFCD01076138
PubChem ID
3641061
Melting Point
215 - 231 °C
Appearance
Gray or off-white powder
Optical Rotation
[a]20D = -2.7 to -4.7 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid g-[b-(5-naphthyl sulfonic acid)-ethylenediamine] ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex structures with high purity.
  • Drug Development: It is used in the design of pharmaceutical compounds, especially in targeting specific biological pathways, enhancing the efficacy of drug candidates in treating various diseases.
  • Bioconjugation: The chemical is effective in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in developing diagnostic tools and targeted therapies.
  • Fluorescent Probes: Its unique structure allows it to be used in the development of fluorescent probes for biological imaging, helping researchers visualize cellular processes in real-time.
  • Research in Neurobiology: The compound is also applied in neurobiology studies, aiding in the exploration of glutamate receptors and their role in synaptic transmission, which is vital for understanding neurological disorders.

Citations