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Catalog Number:
03985
CAS Number:
7536-59-6
Boc-L-glutamic acid े-benzyl ester ॅ-4-nitrophenyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Glu(OBzl)-ONp
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Product Information

Boc-L-glutamic acid g-benzyl ester a-4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This compound features a protective Boc (tert-butyloxycarbonyl) group, which is crucial for the selective protection of amino acids during synthesis. Its unique structure, incorporating both a benzyl ester and a 4-nitrophenyl moiety, enhances its reactivity and makes it an excellent candidate for the development of bioactive peptides and pharmaceuticals. Researchers appreciate its ability to facilitate the introduction of functional groups, allowing for the creation of complex molecular architectures.

In practical applications, Boc-L-glutamic acid g-benzyl ester a-4-nitrophenyl ester is particularly valuable in the synthesis of peptide-based drugs, where precise control over amino acid sequences is essential. Its stability under various reaction conditions and compatibility with a range of coupling reagents make it a preferred choice for chemists aiming to optimize their synthetic pathways. This compound not only streamlines the synthesis process but also contributes to the efficiency and effectiveness of developing new therapeutic agents.

Synonyms
Boc-L-Glu(OBzl)-ONp
CAS Number
7536-59-6
Purity
≥ 98% (HPLC)
Molecular Formula
C23H26N2O8
Molecular Weight
458.47
MDL Number
MFCD00038124
PubChem ID
3635918
Melting Point
115 - 121 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -32 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Glu(OBzl)-ONp
CAS Number
7536-59-6
Purity
≥ 98% (HPLC)
Molecular Formula
C23H26N2O8
Molecular Weight
458.47
MDL Number
MFCD00038124
PubChem ID
3635918
Melting Point
115 - 121 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -32 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-glutamic acid g-benzyl ester a-4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in creating complex structures that require specific amino acid sequences.
  • Drug Development: It is used in the pharmaceutical industry for the development of prodrugs, which enhance the bioavailability of active pharmaceutical ingredients.
  • Bioconjugation: The compound is valuable in bioconjugation processes, allowing researchers to attach biomolecules to drugs or imaging agents, improving targeting and efficacy.
  • Research in Neuroscience: It plays a role in studies related to neurotransmitter pathways, helping scientists understand the mechanisms of synaptic transmission and potential therapeutic targets.
  • Analytical Chemistry: This chemical is utilized in various analytical techniques, such as chromatography, to separate and identify complex mixtures, aiding in quality control and research applications.

Citations