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Catalog Number:
03845
CAS Number:
4666-16-4
Z-L-glutamic acid g-tert-butyl ester a-N-hydroxysuccinimide ester
Purity:
≥ 97% (HPLC)
Synonym(s):
Z-L-Glu(OtBu)-OSu
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Product Information

Z-L-glutamic acid g-tert-butyl ester a-N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound serves as a valuable building block in the formation of peptide bonds, making it essential for researchers in the fields of biochemistry and medicinal chemistry. Its unique structure allows for enhanced stability and solubility, which are critical factors in the formulation of pharmaceuticals. The tert-butyl ester group provides protection for the carboxylic acid functionality, facilitating selective reactions and improving yields during synthesis.

In addition to its role in peptide synthesis, this compound is also employed in the development of targeted drug delivery systems. Its ability to form stable conjugates with various biomolecules enhances the efficacy of therapeutic agents, making it a preferred choice for researchers focused on innovative drug formulations. The compound's favorable properties, such as its compatibility with various solvents and reagents, further support its application in complex chemical reactions, positioning it as a key player in advancing pharmaceutical research and development.

Synonyms
Z-L-Glu(OtBu)-OSu
CAS Number
4666-16-4
Purity
≥ 97% (HPLC)
Molecular Formula
C21H26N2O8
Molecular Weight
434.5
MDL Number
MFCD00153329
PubChem ID
3330961
Melting Point
104-112º C
Optical Rotation
+32.5±1º (c=1.016% in MeOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Z-L-Glu(OtBu)-OSu
CAS Number
4666-16-4
Purity
≥ 97% (HPLC)
Molecular Formula
C21H26N2O8
Molecular Weight
434.5
MDL Number
MFCD00153329
PubChem ID
3330961
Melting Point
104-112º C
Optical Rotation
+32.5±1º (c=1.016% in MeOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-L-glutamic acid g-tert-butyl ester a-N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, which are essential in drug development and biochemistry. Its unique structure allows for the formation of stable peptide bonds, making it ideal for creating complex molecules.
  • Drug Delivery Systems: It is employed in the formulation of drug delivery systems, particularly in the development of prodrugs. These compounds enhance the solubility and bioavailability of therapeutic agents, improving their effectiveness in medical applications.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach biomolecules to drugs or imaging agents. This application is crucial in targeted therapy and diagnostic imaging, allowing for more precise treatment options.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research for their potential neuroprotective effects. This application is significant in developing treatments for neurodegenerative diseases.
  • Cosmetic Formulations: The compound finds use in cosmetic formulations, particularly in anti-aging products. Its ability to enhance skin penetration and stability of active ingredients makes it valuable in the beauty industry.

Citations