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Catalog Number:
03788
CAS Number:
32886-55-8
Boc-L-glutamic acid े-tert-butyl ester ॅ-N-hydroxysuccinimide ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Glu(OtBu)-OSu
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Product Information

Boc-L-glutamic acid g-tert-butyl ester a-N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a Boc (tert-butoxycarbonyl) protecting group, which is essential for the selective protection of amino acids during synthetic processes. Its unique structure allows for the efficient formation of peptide bonds, making it an invaluable tool for researchers in the fields of medicinal chemistry and drug development. The presence of the N-hydroxysuccinimide moiety enhances its reactivity, facilitating the conjugation of biomolecules such as proteins and peptides, which is crucial for the development of targeted therapies and diagnostic agents.

In addition to its role in peptide synthesis, Boc-L-glutamic acid g-tert-butyl ester a-N-hydroxysuccinimide ester is also employed in the preparation of various derivatives that can be used in the design of novel therapeutics. Its stability and ease of use make it a preferred choice among professionals looking to streamline their synthetic pathways. This compound not only improves the efficiency of chemical reactions but also allows for greater control over the final product's properties, making it a significant asset in both academic and industrial laboratories.

Synonyms
Boc-L-Glu(OtBu)-OSu
CAS Number
32886-55-8
Purity
≥ 99% (HPLC)
Molecular Formula
C18H28N2O8
Molecular Weight
400.4
MDL Number
MFCD00153303
PubChem ID
74765075
Melting Point
140 - 150 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -31.5 ± 2 º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Glu(OtBu)-OSu
CAS Number
32886-55-8
Purity
≥ 99% (HPLC)
Molecular Formula
C18H28N2O8
Molecular Weight
400.4
MDL Number
MFCD00153303
PubChem ID
74765075
Melting Point
140 - 150 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -31.5 ± 2 º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-glutamic acid g-tert-butyl ester a-N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific biological activities.
  • Drug Development: It is used in the formulation of prodrugs, which enhance the bioavailability of therapeutic agents, making them more effective in treating various conditions.
  • Bioconjugation: The compound facilitates the attachment of biomolecules to surfaces or other molecules, which is crucial in developing targeted drug delivery systems and diagnostic tools.
  • Research in Neuroscience: Its derivatives are being explored for their potential in neuropharmacology, helping to understand and treat neurological disorders.
  • Polymer Chemistry: This chemical is also applied in the creation of functional polymers, which can be used in various applications, including drug delivery and tissue engineering.

Citations