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Catalog Number:
03787
CAS Number:
24277-39-2
Boc-L-glutamic acid ॅ-tert-butyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Glu-OtBu
Documents
$22.03 /1G
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Product Information

Boc-L-glutamic acid a-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected form of L-glutamic acid offers enhanced stability and solubility, making it an ideal choice for researchers looking to develop bioactive peptides and drug candidates. Its unique tert-butyl ester group provides a protective mechanism that facilitates the selective functionalization of the amino acid, allowing for the efficient assembly of complex peptide structures.

In addition to its applications in organic synthesis, Boc-L-glutamic acid a-tert-butyl ester is also valuable in the development of various therapeutic agents, particularly in the fields of oncology and neurology. Researchers appreciate its ability to improve the pharmacokinetic properties of peptides, leading to enhanced bioavailability and efficacy. With its favorable characteristics, this compound stands out as a crucial building block for innovative drug development and bioconjugation strategies.

Synonyms
Boc-L-Glu-OtBu
CAS Number
24277-39-2
Purity
≥ 98% (HPLC)
Molecular Formula
C14H25NO6
Molecular Weight
303.36
MDL Number
MFCD00038273
PubChem ID
295484
Melting Point
111 - 114 °C
Appearance
White powder
Optical Rotation
[a]20D = -17 ± 2 ° (C=1 in EtOAc)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Boc-L-Glu-OtBu
CAS Number
24277-39-2
Purity
≥ 98% (HPLC)
Molecular Formula
C14H25NO6
Molecular Weight
303.36
MDL Number
MFCD00038273
PubChem ID
295484
Melting Point
111 - 114 °C
Appearance
White powder
Optical Rotation
[a]20D = -17 ± 2 ° (C=1 in EtOAc)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-glutamic acid a-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for amino acids during peptide synthesis, allowing for the selective modification of other functional groups without interfering with the glutamic acid residue.
  • Drug Development: It plays a crucial role in the design of pharmaceuticals, particularly in the development of prodrugs that enhance bioavailability and stability, making it easier to deliver therapeutic agents effectively.
  • Biotechnology: In the field of biotechnology, it is used in the production of peptide-based vaccines, where the protected amino acid can be incorporated into larger peptide chains to elicit immune responses.
  • Research in Neuroscience: The compound is valuable in neuroscience research for studying glutamate receptors, which are essential for synaptic transmission and plasticity, providing insights into neurological disorders.
  • Analytical Chemistry: It is employed in analytical methods to identify and quantify amino acids in complex mixtures, aiding researchers in characterizing biological samples and understanding metabolic pathways.

Citations