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Catalog Number:
03752
CAS Number:
101214-22-6
Fmoc-L-glutamic acid े-tert-butyl ester ॅ-N-hydroxysuccinimide ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Glu(OtBu)-OSu
Documents
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Product Information

Fmoc-L-glutamic acid g-tert-butyl ester a-N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is essential for the selective protection of amino acids during the synthesis of peptides. Its unique structure allows for the efficient coupling with various amines, making it an ideal choice for researchers looking to create complex peptide sequences or modify existing peptides for enhanced functionality.

The compound's N-hydroxysuccinimide ester functionality further enhances its reactivity, facilitating the formation of stable amide bonds with primary amines. This property is particularly beneficial in drug development and the creation of targeted therapeutics, where precise modifications are crucial. Additionally, the tert-butyl ester group provides stability under various conditions, ensuring that the compound remains effective throughout the synthesis process. Researchers and industry professionals can leverage this compound to streamline their workflows and achieve high yields in peptide synthesis and bioconjugation projects.

Synonyms
Fmoc-L-Glu(OtBu)-OSu
CAS Number
101214-22-6
Purity
≥ 98% (HPLC)
Molecular Formula
C28H30N2O6
Molecular Weight
522.55
MDL Number
MFCD00235812
PubChem ID
59153986
Melting Point
159 - 166 °C
Appearance
White powder
Optical Rotation
[a]D20 = -29 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Glu(OtBu)-OSu
CAS Number
101214-22-6
Purity
≥ 98% (HPLC)
Molecular Formula
C28H30N2O6
Molecular Weight
522.55
MDL Number
MFCD00235812
PubChem ID
59153986
Melting Point
159 - 166 °C
Appearance
White powder
Optical Rotation
[a]D20 = -29 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid g-tert-butyl ester a-N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create custom sequences for various applications in drug development and biotechnology.
  • Bioconjugation: Its reactive N-hydroxysuccinimide (NHS) group enables efficient conjugation to proteins or other biomolecules, facilitating the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: The compound can be incorporated into drug delivery vehicles, enhancing the stability and bioavailability of therapeutic agents, particularly in cancer treatments.
  • Research in Neuroscience: By modifying glutamic acid, it aids in studying neurotransmitter pathways, contributing to the understanding of neurological disorders and potential treatments.
  • Material Science: Its unique properties allow for the development of novel materials with specific functionalities, such as hydrogels for tissue engineering applications.

Citations