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Catalog Number:
03639
CAS Number:
144120-54-7
Fmoc-L-glutamic acid ॅ-allyl ester
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Glu-OAll
Documents
$35.30 /1G
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Product Information

Fmoc-L-glutamic acid a-allyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which facilitates the selective coupling of amino acids in solid-phase peptide synthesis, making it an essential building block for researchers in the fields of biochemistry and medicinal chemistry. Its a-allyl ester functionality enhances its reactivity, allowing for efficient transformations and modifications, which are crucial in the development of complex peptide structures.

In addition to its role in peptide synthesis, Fmoc-L-glutamic acid a-allyl ester is also valuable in the design of bioactive compounds and pharmaceuticals. Its unique properties enable chemists to explore various modifications that can lead to improved biological activity and specificity. Researchers appreciate its stability and ease of handling, making it a preferred choice for those looking to streamline their synthesis processes while achieving high yields and purity.

Synonyms
Fmoc-L-Glu-OAll
CAS Number
144120-54-7
Purity
≥ 97% (HPLC)
Molecular Formula
C23H23NO6
Molecular Weight
409.43
MDL Number
MFCD00467718
PubChem ID
3425156
Melting Point
118 - 133 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -20 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Glu-OAll
CAS Number
144120-54-7
Purity
≥ 97% (HPLC)
Molecular Formula
C23H23NO6
Molecular Weight
409.43
MDL Number
MFCD00467718
PubChem ID
3425156
Melting Point
118 - 133 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -20 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid a-allyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for drug development and biological studies.
  • Drug Design: Its unique structure makes it valuable in the design of new pharmaceuticals, particularly in targeting specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The allyl ester functionality enables easy conjugation with various biomolecules, facilitating the development of targeted drug delivery systems.
  • Research in Neuroscience: It is used to study glutamate receptors, which play a crucial role in neurotransmission, helping researchers understand neurological disorders.
  • Polymer Chemistry: This compound can be incorporated into polymer matrices, enhancing material properties for applications in drug delivery and tissue engineering.

Citations