Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
33078
CAS Number:
159680-21-4
Fmoc-L-Cys(Phacm)-OH
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
-(9-Fluorenylmethyloxycarbonyl)-S-Phenylacetylaminomethyl)-L-cysteine
Documents
$65.40 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-L-Cys(Phacm)-OH is a valuable compound widely utilized in peptide synthesis and drug development. This protected form of cysteine features a fluorenylmethyloxycarbonyl (Fmoc) group, which facilitates the selective introduction of cysteine residues into peptides while maintaining stability during synthesis. Its unique Phacm (phenylacetamidomethyl) protection enhances the compound's reactivity and compatibility with various coupling reagents, making it an ideal choice for researchers focused on creating complex peptide structures.

This compound is particularly relevant in the fields of medicinal chemistry and biochemistry, where it is employed in the design of peptide-based therapeutics and in the study of protein interactions. Its ability to form disulfide bonds upon deprotection allows for the stabilization of peptide structures, which is crucial for developing effective drugs. Researchers appreciate its ease of use and the high purity it offers, ensuring reliable results in experimental applications. Fmoc-L-Cys(Phacm)-OH stands out for its versatility and efficiency in peptide synthesis, making it an essential tool for professionals in the pharmaceutical and biotechnology industries.

Synonyms
-(9-Fluorenylmethyloxycarbonyl)-S-Phenylacetylaminomethyl)-L-cysteine
CAS Number
159680-21-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C27H26N2O5S
Molecular Weight
490.6
MDL Number
MFCD00797550
PubChem ID
78076237
Melting Point
157 - 159 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = - 36 ± 2 ° (C=1 in DMF)
Conditions
Store at 2-8°C
General Information
Synonyms
-(9-Fluorenylmethyloxycarbonyl)-S-Phenylacetylaminomethyl)-L-cysteine
CAS Number
159680-21-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C27H26N2O5S
Molecular Weight
490.6
MDL Number
MFCD00797550
PubChem ID
78076237
Melting Point
157 - 159 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = - 36 ± 2 ° (C=1 in DMF)
Conditions
Store at 2-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-Cys(Phacm)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of cysteine residues, which are crucial for forming disulfide bonds in proteins.
  • Drug Development: It plays a significant role in the development of peptide-based drugs, offering advantages in stability and bioactivity, which are essential for therapeutic applications.
  • Bioconjugation: The unique functional groups in this compound facilitate bioconjugation processes, enabling the attachment of drugs or imaging agents to proteins, enhancing their efficacy and targeting capabilities.
  • Research in Protein Engineering: Researchers utilize it to modify proteins, allowing for the exploration of structure-function relationships and the development of novel protein variants with improved properties.
  • Diagnostics: Its application in creating peptide-based assays aids in the development of diagnostic tools, which can be used for disease detection and monitoring, providing timely and accurate results.

Citations