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Catalog Number:
31113
CAS Number:
252206-29-4
Fmoc-S-4-methyltrityl-D-cysteine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Cys(Mtt)-OH
Documents
$43.87 /1G
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Product Information

Fmoc-S-4-methyltrityl-D-cysteine is a valuable building block in peptide synthesis, particularly favored for its protective group that facilitates the selective modification of cysteine residues. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its stability under various reaction conditions, making it ideal for solid-phase peptide synthesis. Its unique structure, characterized by the presence of a 4-methyltrityl group, enhances the compound's hydrophobicity, allowing for improved solubility and stability in organic solvents.

Researchers and industry professionals utilize Fmoc-S-4-methyltrityl-D-cysteine in the development of peptide-based therapeutics and bioconjugates, where precise control over cysteine functionality is crucial. Its application extends to the synthesis of peptide ligands for drug delivery systems and the creation of novel biomaterials. The compound's ability to undergo selective deprotection under mild conditions further enhances its utility in complex peptide assembly, making it a preferred choice for chemists seeking efficiency and reliability in their synthetic pathways.

Synonyms
Fmoc-D-Cys(Mtt)-OH
CAS Number
252206-29-4
Purity
≥ 99% (HPLC)
Molecular Formula
C38H33NO4S
Molecular Weight
599.75
MDL Number
MFCD14155676
PubChem ID
76401334
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -20 ± 2º (C=2 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Cys(Mtt)-OH
CAS Number
252206-29-4
Purity
≥ 99% (HPLC)
Molecular Formula
C38H33NO4S
Molecular Weight
599.75
MDL Number
MFCD14155676
PubChem ID
76401334
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -20 ± 2º (C=2 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-4-methyltrityl-D-cysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it ideal for complex peptide sequences.
  • Drug Development: Researchers employ this chemical in the development of peptide-based pharmaceuticals, enhancing the efficacy and stability of drug candidates, particularly in targeting specific biological pathways.
  • Bioconjugation: It is used in bioconjugation processes to attach biomolecules to surfaces or other molecules, facilitating the creation of targeted drug delivery systems and diagnostic tools.
  • Research in Cancer Therapy: The compound is explored in the design of novel anticancer agents, leveraging its ability to modify peptide structures that can selectively target cancer cells.
  • Protein Engineering: This chemical aids in the engineering of proteins with desired properties, contributing to advancements in biotechnology and synthetic biology applications.

Citations