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Catalog Number:
16183
CAS Number:
157355-80-1
Fmoc-D-cysteine hydrate
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Cys-OH·H2O
Documents
$55.48 /100MG
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Product Information

Fmoc-D-cysteine hydrate is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of cysteine residues in the formation of peptides. Its unique structure allows for the introduction of thiol groups, making it an essential building block in the development of peptide-based therapeutics and biomaterials. Researchers appreciate its stability and ease of handling, which contribute to efficient synthesis processes.

In addition to its role in peptide synthesis, Fmoc-D-cysteine hydrate is also employed in the preparation of functionalized surfaces and drug delivery systems, enhancing the bioactivity and targeting capabilities of therapeutic agents. Its ability to form disulfide bonds further expands its utility in creating complex molecular architectures. With its broad applicability in pharmaceutical research and development, Fmoc-D-cysteine hydrate stands out as a crucial tool for scientists aiming to innovate in the fields of drug design and biomolecular engineering.

Synonyms
Fmoc-D-Cys-OH·H2O
CAS Number
157355-80-1
Purity
≥ 98% (HPLC)
Molecular Formula
C18H17NO4S·H2O
Molecular Weight
361.5
MDL Number
MFCD18253022
PubChem ID
11350927
Melting Point
113 - 119 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 25 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Cys-OH·H2O
CAS Number
157355-80-1
Purity
≥ 98% (HPLC)
Molecular Formula
C18H17NO4S·H2O
Molecular Weight
361.5
MDL Number
MFCD18253022
PubChem ID
11350927
Melting Point
113 - 119 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 25 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-cysteine hydrate is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of cysteine residues which are crucial for forming disulfide bonds.
  • Drug Development: It plays a significant role in the development of pharmaceuticals, especially in creating peptide-based drugs that can target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The unique properties of Fmoc-D-cysteine hydrate enable its use in bioconjugation processes, allowing researchers to attach biomolecules like antibodies or enzymes to surfaces or other molecules, improving drug delivery systems.
  • Protein Engineering: This compound is essential in protein engineering, where it aids in the modification of proteins to enhance their stability and functionality, which is vital in various biotechnological applications.
  • Analytical Chemistry: It is utilized in analytical methods for detecting and quantifying thiol-containing compounds, providing valuable insights in biochemical research and quality control in pharmaceuticals.

Citations