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Catalog Number:
12605
CAS Number:
623177-62-8
Fmoc-L-cysteine amide
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-L-Cys-NH2, Nα-Fmoc-L-cysteinamide
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Product Information

Fmoc-L-cysteine amide is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of the amino group during solid-phase peptide synthesis. Its unique structure allows for the incorporation of cysteine into peptides, facilitating the formation of disulfide bonds that are crucial for stabilizing protein structures. Researchers and industry professionals appreciate its role in the development of therapeutic peptides and proteins, particularly in drug design and delivery systems.

In addition to its applications in peptide synthesis, Fmoc-L-cysteine amide is also valuable in the field of materials science, where it can be used to create functionalized surfaces and nanomaterials. Its ability to form stable conjugates makes it an excellent choice for creating targeted drug delivery systems and biosensors. With its favorable properties and broad applicability, Fmoc-L-cysteine amide stands out as a key compound for researchers looking to enhance their work in biochemistry and pharmaceutical development.

Synonyms
Fmoc-L-Cys-NH2, Nα-Fmoc-L-cysteinamide
CAS Number
623177-62-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H18N2O3S
Molecular Weight
342.4
MDL Number
MFCD03788160
PubChem ID
10382760
Melting Point
169 - 171 °C
Appearance
White to off-white powder
Optical Rotation
[a]25D = -4.5 ± 1 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Cys-NH2, Nα-Fmoc-L-cysteinamide
CAS Number
623177-62-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H18N2O3S
Molecular Weight
342.4
MDL Number
MFCD03788160
PubChem ID
10382760
Melting Point
169 - 171 °C
Appearance
White to off-white powder
Optical Rotation
[a]25D = -4.5 ± 1 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-cysteine amide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a critical building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of cysteine residues, which are essential for forming disulfide bonds in proteins.
  • Drug Development: Its application in medicinal chemistry aids in the design of cysteine-containing compounds that can act as potential therapeutics, particularly in targeting diseases where cysteine plays a role in the biological mechanism.
  • Bioconjugation: Fmoc-L-cysteine amide is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial for developing biosensors and targeted drug delivery systems.
  • Research on Protein Folding: The compound is valuable in studies related to protein folding and stability, helping researchers understand how cysteine residues influence protein structure and function.
  • Antioxidant Research: Its properties allow for exploration in antioxidant studies, where cysteine's thiol group can be investigated for its ability to scavenge free radicals, contributing to the development of new antioxidant therapies.

Citations