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Catalog Number:
05693
CAS Number:
200354-41-2
Fmoc-S-4-methylbenzyl-D-cysteine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Cys(pMeBzl)-OH
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$113.87 /1G
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Product Information

Fmoc-S-4-methylbenzyl-D-cysteine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a 4-methylbenzyl group, enhances its stability and solubility, making it an excellent choice for researchers in the fields of medicinal chemistry and biochemistry.

In practical applications, Fmoc-S-4-methylbenzyl-D-cysteine is particularly valuable in the synthesis of complex peptides and proteins, allowing for the incorporation of sulfur-containing amino acids that can impart unique properties to the final product. This compound is also instrumental in developing therapeutics targeting various diseases, including cancer and neurodegenerative disorders, due to its ability to facilitate the formation of disulfide bonds in peptide structures. Its high purity and reliability make it a preferred choice for professionals seeking to optimize their synthetic routes and enhance the efficacy of their research outcomes.

Synonyms
Fmoc-D-Cys(pMeBzl)-OH
CAS Number
200354-41-2
Purity
≥ 98% (HPLC)
Molecular Formula
C26H25NO4S
Molecular Weight
447.6
MDL Number
MFCD00237013
PubChem ID
5140893
Melting Point
152-157 °C
Appearance
White powder
Optical Rotation
[a]D20 = +34 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Cys(pMeBzl)-OH
CAS Number
200354-41-2
Purity
≥ 98% (HPLC)
Molecular Formula
C26H25NO4S
Molecular Weight
447.6
MDL Number
MFCD00237013
PubChem ID
5140893
Melting Point
152-157 °C
Appearance
White powder
Optical Rotation
[a]D20 = +34 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-4-methylbenzyl-D-cysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptides with specific functionalities.
  • Drug Development: It plays a significant role in the development of peptide-based pharmaceuticals, offering potential therapeutic benefits due to its unique structural properties that can enhance drug efficacy.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, facilitating the creation of targeted drug delivery systems.
  • Research in Cancer Therapy: Its application in cancer research is notable, as it can be incorporated into compounds designed to selectively target cancer cells, potentially leading to more effective treatments with fewer side effects.
  • Protein Engineering: The compound is valuable in protein engineering, where it aids in the modification of proteins to improve their stability and activity, which is crucial for various biotechnological applications.

Citations