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Catalog Number:
03700
CAS Number:
168300-88-7
Fmoc-S-acetamidomethyl-D-cysteine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-Cys(Acm)-OH
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Product Information

Fmoc-S-acetamidomethyl-D-cysteine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its ability to protect the thiol group of cysteine during the synthesis of peptides, allowing for the selective incorporation of this important amino acid into complex structures. Its unique Fmoc (fluorenylmethyloxycarbonyl) protecting group provides stability and ease of removal under mild conditions, making it an ideal choice for researchers focused on developing novel therapeutics or studying protein interactions.

In addition to its applications in peptide synthesis, Fmoc-S-acetamidomethyl-D-cysteine is also utilized in the development of bioconjugates and targeted drug delivery systems. Its ability to form disulfide bonds enhances the stability of peptide-based drugs, which is crucial for their efficacy in biological systems. Researchers in medicinal chemistry and biochemistry will find this compound invaluable for its reliability and effectiveness in producing high-purity peptides with specific functionalities.

Synonyms
Fmoc-D-Cys(Acm)-OH
CAS Number
168300-88-7
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C21H22N2O5S
Molecular Weight
414.5
MDL Number
MFCD00077053
PubChem ID
4021455
Melting Point
119 - 122 ºC
Appearance
White powder
Optical Rotation
[a]D20 = 32 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Cys(Acm)-OH
CAS Number
168300-88-7
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C21H22N2O5S
Molecular Weight
414.5
MDL Number
MFCD00077053
PubChem ID
4021455
Melting Point
119 - 122 ºC
Appearance
White powder
Optical Rotation
[a]D20 = 32 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-acetamidomethyl-D-cysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, which are increasingly important in treating various diseases, including cancer and metabolic disorders.
  • Bioconjugation: The compound is used in bioconjugation techniques, enabling the attachment of peptides to other biomolecules, which is essential for creating targeted drug delivery systems.
  • Research in Protein Engineering: It aids in the modification of proteins to enhance their stability and functionality, which is vital for various applications in biotechnology and pharmaceuticals.
  • Diagnostics: This chemical is utilized in the development of diagnostic tools, such as biosensors, where modified peptides can improve the sensitivity and specificity of detection methods.

Citations