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Catalog Number:
05681
CAS Number:
119062-05-4
Fmoc-L-aspartic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Asp-OH
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Product Information

Fmoc-L-aspartic acid is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for creating complex peptides. Its unique structure not only enhances stability but also improves solubility in organic solvents, facilitating various applications in both research and industrial settings. Researchers often leverage Fmoc-L-aspartic acid in the development of peptide-based therapeutics, including those targeting neurological disorders and cancer, due to its ability to mimic natural amino acids while providing additional functional benefits.

The compound's high purity and reliable performance make it a preferred choice among chemists and biochemists. Its application extends to the synthesis of peptide libraries for drug discovery, where it plays a crucial role in identifying potential therapeutic candidates. Additionally, Fmoc-L-aspartic acid is instrumental in the production of peptide conjugates and bioconjugates, enhancing the efficacy of drug delivery systems. With its proven track record in facilitating innovative research and development, Fmoc-L-aspartic acid stands out as a key reagent for professionals in the pharmaceutical and biotechnology industries.

Synonyms
Fmoc-L-Asp-OH
CAS Number
119062-05-4
Purity
≥ 98% (HPLC)
Molecular Formula
C19H17NO6
Molecular Weight
355.35
MDL Number
MFCD00237654
PubChem ID
3671531
Melting Point
186 - 192 °C (Lit.)
Appearance
White powder
Optical Rotation
[a]D20 = -30 ± 2 º (C = 1 in DMF) (Lit.)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asp-OH
CAS Number
119062-05-4
Purity
≥ 98% (HPLC)
Molecular Formula
C19H17NO6
Molecular Weight
355.35
MDL Number
MFCD00237654
PubChem ID
3671531
Melting Point
186 - 192 °C (Lit.)
Appearance
White powder
Optical Rotation
[a]D20 = -30 ± 2 º (C = 1 in DMF) (Lit.)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-aspartic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for amino acids during peptide synthesis, allowing for the selective modification of specific sites without affecting others.
  • Drug Development: It plays a crucial role in the design of peptide-based pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Bioconjugation: Fmoc-L-aspartic acid is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, enhancing the functionality of therapeutic agents.
  • Research in Protein Engineering: Researchers utilize this compound to create modified proteins with enhanced stability and activity, which are essential for various biotechnological applications.
  • Diagnostic Applications: It is also applied in the development of diagnostic tools, particularly in assays that require specific peptide interactions, improving the accuracy of disease detection.

Citations