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Catalog Number:
03842
CAS Number:
3338-32-7
Z-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Z-L-Asp(OtBu)-OSu
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Product Information

Z-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound serves as a valuable building block in the production of peptide-based pharmaceuticals, particularly in the creation of prodrugs that enhance bioavailability and stability. Its unique structure allows for selective reactions, making it an ideal choice for researchers looking to develop targeted therapies. The tert-butyl ester group provides increased lipophilicity, facilitating better membrane permeability, which is crucial in drug formulation.

In addition to its applications in medicinal chemistry, Z-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester is also employed in various biochemical assays and research studies. Its ability to act as a coupling agent in peptide synthesis allows for efficient formation of peptide bonds, streamlining the process for researchers. This compound stands out for its stability and ease of use, making it a preferred choice among professionals in the pharmaceutical and biotechnology industries.

Synonyms
Z-L-Asp(OtBu)-OSu
CAS Number
3338-32-7
Purity
≥ 98% (HPLC)
Molecular Formula
C20H24N2O8
Molecular Weight
420.4
MDL Number
MFCD00153328
PubChem ID
102986
Melting Point
148-157º C
Appearance
White to off-white powder
Optical Rotation
-19 to -21º (c=1 in Dioxane)
Conditions
Store at 0-8°C
General Information
Synonyms
Z-L-Asp(OtBu)-OSu
CAS Number
3338-32-7
Purity
≥ 98% (HPLC)
Molecular Formula
C20H24N2O8
Molecular Weight
420.4
MDL Number
MFCD00153328
PubChem ID
102986
Melting Point
148-157º C
Appearance
White to off-white powder
Optical Rotation
-19 to -21º (c=1 in Dioxane)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Z-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for drug development and therapeutic applications.
  • Drug Delivery Systems: It is used in formulating drug delivery systems, enhancing the stability and bioavailability of pharmaceuticals, which is crucial for effective treatment regimens.
  • Bioconjugation: The compound facilitates bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, thereby improving targeting and efficacy in cancer therapies.
  • Research in Neuroscience: Its derivatives are explored in neuroscience for developing compounds that can modulate neurotransmitter activity, potentially leading to new treatments for neurological disorders.
  • Polymer Chemistry: This chemical plays a role in the development of novel polymers with specific properties, which can be applied in various industries, including materials science and biotechnology.

Citations