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Catalog Number:
03905
CAS Number:
144317-22-6
Nα-Fmoc-Nγ-4-methyltrityl-L-asparagine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Asn(Mtt)-OH
Documents
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Product Information

Na-Fmoc-Ng-4-methyltrityl-L-asparagine is a highly versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of the amino group during solid-phase peptide synthesis. Its unique structure, characterized by the presence of a 4-methyltrityl group, enhances the stability and solubility of peptides, making it an excellent choice for researchers looking to optimize their synthesis processes.

In practical applications, Na-Fmoc-Ng-4-methyltrityl-L-asparagine is particularly valuable in the pharmaceutical industry for the development of peptide-based therapeutics. Its ability to facilitate the formation of complex peptide structures allows for the exploration of novel drug candidates with improved efficacy and specificity. Additionally, this compound's compatibility with various coupling reagents and its ease of deprotection make it a preferred choice for chemists engaged in advanced peptide synthesis. Whether you are developing new therapeutics or conducting research in biochemistry, this compound offers significant advantages in terms of efficiency and versatility.

Synonyms
Fmoc-L-Asn(Mtt)-OH
CAS Number
144317-22-6
Purity
≥ 99% (HPLC)
Molecular Formula
C39H34N2O5
Molecular Weight
610.72
MDL Number
MFCD00237160
PubChem ID
76401348
Melting Point
192-196 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D24 = -13.5 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Asn(Mtt)-OH
CAS Number
144317-22-6
Purity
≥ 99% (HPLC)
Molecular Formula
C39H34N2O5
Molecular Weight
610.72
MDL Number
MFCD00237160
PubChem ID
76401348
Melting Point
192-196 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D24 = -13.5 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ng-4-methyltrityl-L-asparagine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex and functional peptide sequences for various applications in biochemistry and pharmacology.
  • Drug Development: Its role in drug design is significant, particularly in developing peptide-based therapeutics, which can lead to more effective treatments with fewer side effects compared to traditional small-molecule drugs.
  • Protein Engineering: This chemical is used in modifying proteins to enhance their stability and activity, which is crucial for creating more efficient enzymes and therapeutic proteins in industrial biotechnology.
  • Bioconjugation: It facilitates the attachment of biomolecules to other compounds, enabling the development of targeted drug delivery systems that improve the efficacy of treatments in cancer therapy.
  • Research in Neuroscience: By aiding in the synthesis of neuropeptides, it contributes to studies investigating neurological functions and potential treatments for neurodegenerative diseases.

Citations