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Catalog Number:
16940
CAS Number:
1135616-49-7
Nα-Fmoc-Nω-methyl-Nω'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Arg(Me,Pbf)-OH
Documents
$160.00 /100MG
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Product Information

Na-Fmoc-Nw-methyl-Nw'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is widely used in solid-phase peptide synthesis due to its stability and ease of removal. The incorporation of the pentamethyldihydrobenzofuran sulfonyl moiety enhances its specificity and reactivity, making it an excellent choice for researchers focused on developing targeted therapeutics and complex peptide structures.

In practical applications, this compound is particularly valuable in the fields of medicinal chemistry and biochemistry, where it can be utilized to create peptides with enhanced biological activity or selectivity. Its unique structure allows for the exploration of novel therapeutic pathways, especially in the development of peptide-based drugs. Researchers can leverage its properties to design innovative solutions for various health challenges, making it a vital tool in the ongoing quest for effective treatments.

Synonyms
Fmoc-L-Arg(Me,Pbf)-OH
CAS Number
1135616-49-7
Purity
≥ 99% (HPLC)
Molecular Formula
C35H42N4O7S
Molecular Weight
662.8
MDL Number
MFCD08064312
PubChem ID
59602026
Appearance
White to off-white or light yellowish powder
Optical Rotation
[a]D20 = -56 ± 2 ° (C=0.1 in DCM)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Arg(Me,Pbf)-OH
CAS Number
1135616-49-7
Purity
≥ 99% (HPLC)
Molecular Formula
C35H42N4O7S
Molecular Weight
662.8
MDL Number
MFCD08064312
PubChem ID
59602026
Appearance
White to off-white or light yellowish powder
Optical Rotation
[a]D20 = -56 ± 2 ° (C=0.1 in DCM)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nw-methyl-Nw'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others, which is crucial in developing complex biomolecules.
  • Drug Development: It plays a significant role in the pharmaceutical industry for designing novel therapeutic agents, particularly in targeting specific biological pathways due to its unique structural features.
  • Bioconjugation: Researchers use this chemical to create bioconjugates, which are essential in developing targeted drug delivery systems, enhancing the efficacy of treatments while minimizing side effects.
  • Protein Engineering: The compound is valuable in modifying proteins to improve their stability and activity, which is vital for applications in biotechnology and enzyme engineering.
  • Analytical Chemistry: It is employed in various analytical techniques to study protein interactions and dynamics, aiding researchers in understanding biological processes at a molecular level.

Citations