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Catalog Number:
02378
CAS Number:
58111-94-7
Nα-Fmoc-Nω-nitro-L-arginine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Arg(NO2)-OH
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Product Information

Na-Fmoc-Nw-nitro-L-arginine is a highly specialized amino acid derivative that serves as a valuable building block in peptide synthesis and drug development. This compound is particularly notable for its protective Fmoc (fluorenylmethyloxycarbonyl) group, which facilitates the selective modification of amino acids during solid-phase peptide synthesis. Its nitro group enhances the compound's bioactivity, making it an attractive candidate for research in pharmacology and biochemistry. Researchers utilize Na-Fmoc-Nw-nitro-L-arginine in the design of peptides that can modulate biological pathways, particularly in studies related to nitric oxide signaling and cardiovascular health.

In addition to its applications in peptide synthesis, this compound's unique structure allows for the exploration of novel therapeutic agents targeting various diseases. Its ability to serve as a precursor for more complex molecules positions it as a key player in the development of innovative treatments. With its combination of protective and reactive functionalities, Na-Fmoc-Nw-nitro-L-arginine stands out as a versatile tool for researchers aiming to advance their work in medicinal chemistry and related fields.

Synonyms
Fmoc-L-Arg(NO2)-OH
CAS Number
58111-94-7
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23N5O6
Molecular Weight
441.4
MDL Number
MFCD00065617
Melting Point
156 - 158 ?C (dec.)
Appearance
White to off-white powder
Optical Rotation
[a]25D = 12 ± 2 ° (C=1.205 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Arg(NO2)-OH
CAS Number
58111-94-7
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23N5O6
Molecular Weight
441.4
MDL Number
MFCD00065617
Melting Point
156 - 158 ?C (dec.)
Appearance
White to off-white powder
Optical Rotation
[a]25D = 12 ± 2 ° (C=1.205 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nw-nitro-L-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice for researchers in organic chemistry.
  • Biological Research: It is used in studies related to nitric oxide signaling pathways, providing insights into cardiovascular health and potential therapeutic targets for diseases related to nitric oxide dysregulation.
  • Drug Development: The compound's unique structure allows it to be explored as a potential lead compound in the development of new drugs, particularly those targeting metabolic disorders or cardiovascular diseases.
  • Analytical Chemistry: Na-Fmoc-Nw-nitro-L-arginine can be employed as a standard in various analytical techniques, aiding in the quantification and characterization of related compounds in complex mixtures.
  • Bioconjugation: Its reactive functional groups enable the conjugation with biomolecules, facilitating the development of targeted drug delivery systems and improving the efficacy of therapeutic agents.

Citations