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Catalog Number:
00855
CAS Number:
61315-61-5
Nα-Boc-Nω-4-toluenesulfonyl-D-arginine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-D-Arg(Tos)-OH
Documents
$18.53 /1G
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Product Information

Na-Boc-Nw-4-toluenesulfonyl-D-arginine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and bioconjugation applications. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for researchers working in the fields of medicinal chemistry and biochemistry. Its unique structure, characterized by the presence of a toluenesulfonyl group, allows for selective reactions, facilitating the development of complex peptides and proteins with tailored functionalities.

This compound is particularly valuable in the synthesis of peptide-based therapeutics, where precise modifications are essential for achieving desired biological activities. Its ability to serve as a building block in the construction of biologically active peptides opens up avenues for drug development, particularly in targeting specific diseases. Additionally, Na-Boc-Nw-4-toluenesulfonyl-D-arginine can be utilized in the design of enzyme inhibitors and other bioactive molecules, making it a versatile tool for researchers aiming to innovate in drug discovery and development.

Synonyms
Boc-D-Arg(Tos)-OH
CAS Number
61315-61-5
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H28N4O6S
Molecular Weight
428.5
MDL Number
MFCD00038260
Melting Point
107 - 109 ?C
Appearance
White powder
Optical Rotation
[a]D20 = 3.5 ± 1.5 º (C=4 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-D-Arg(Tos)-OH
CAS Number
61315-61-5
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C18H28N4O6S
Molecular Weight
428.5
MDL Number
MFCD00038260
Melting Point
107 - 109 ?C
Appearance
White powder
Optical Rotation
[a]D20 = 3.5 ± 1.5 º (C=4 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nw-4-toluenesulfonyl-D-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial for researchers developing complex peptides for therapeutic applications.
  • Drug Development: It plays a role in the design of novel drugs, particularly in creating inhibitors for specific enzymes. Its ability to modify arginine residues enhances the efficacy of potential drug candidates in treating various diseases.
  • Bioconjugation: The chemical is used in bioconjugation techniques, linking biomolecules to drugs or imaging agents. This is beneficial in the field of targeted therapy, improving the delivery of therapeutic agents to specific cells.
  • Protein Engineering: Researchers utilize this compound to introduce functional groups into proteins, enhancing their stability and activity. This is particularly valuable in the production of therapeutic proteins and enzymes.
  • Diagnostics: It is also applied in the development of diagnostic tools, where its properties can help in the detection of specific biomolecules, aiding in disease diagnosis and monitoring.

Citations