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Catalog Number:
05281
CAS Number:
2483-49-0
Boc-L-alanine-4-nitrophenyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-L-Ala-ONp
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Product Information

Boc-L-alanine-4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This amino acid derivative features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and reactivity, making it an ideal building block for the development of complex peptides and biologically active molecules. Its unique 4-nitrophenyl ester functionality allows for selective cleavage under mild conditions, facilitating the release of the active amino acid during synthesis.

Researchers and industry professionals appreciate Boc-L-alanine-4-nitrophenyl ester for its role in drug development, particularly in the design of peptide-based therapeutics. Its applications extend to the synthesis of enzyme inhibitors, hormone analogs, and other bioactive compounds. The compound's favorable properties, such as high purity and ease of handling, make it a preferred choice for laboratories focused on innovative medicinal chemistry and biochemistry projects.

Synonyms
Boc-L-Ala-ONp
CAS Number
2483-49-0
Purity
≥ 99% (HPLC)
Molecular Formula
C14H18N2O6
Molecular Weight
310.31
MDL Number
MFCD00038117
PubChem ID
102826
Melting Point
82 - 84 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -52 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Ala-ONp
CAS Number
2483-49-0
Purity
≥ 99% (HPLC)
Molecular Formula
C14H18N2O6
Molecular Weight
310.31
MDL Number
MFCD00038117
PubChem ID
102826
Melting Point
82 - 84 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -52 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-alanine-4-nitrophenyl ester is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, enabling researchers to create complex structures for various applications in drug development.
  • Drug Design: Its unique properties allow for the modification of drug candidates, enhancing their efficacy and bioavailability, particularly in the pharmaceutical industry.
  • Bioconjugation: The compound can be used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in developing targeted therapies.
  • Research in Enzyme Inhibition: It is employed in studies aimed at understanding enzyme mechanisms, providing insights that can lead to the development of new inhibitors for therapeutic purposes.
  • Analytical Chemistry: The ester can be utilized in analytical methods to quantify amino acids and peptides, aiding researchers in quality control and formulation development.

Citations